Brief report: Chromosomal analysis of perinatal death in Macaca mulatta and Macaca radiata.

Peripheral blood samples from 53 macaque perinatal deaths at the California Primate Research Center (CPRC) were cultured to produce chromosomes for analysis. Karyotypes were constructed for 26 successful cultures and revealed no apparent chromosomal anomalies. A genetic screening program at primate breeding facilities is important for estimating the frequency of chromosomal anomalies in macaques and for understanding the contribution of chromosomal anomalies to reproductive loss and congenital malformations in macaques.