Halifax Health Hospice, Port Orange, Florida, USA.
Department of Health Sciences Research, Mayo Clinic, Jacksonville, FL, USA.
Am J Hosp Palliat Care. 2020 Aug;37(8):589-593. doi: 10.1177/1049909119900378. Epub 2020 Jan 27.
Palliative medicine physicians are challenged by lack of guidance regarding effectiveness and dosing of cannabis products in the setting of their emerging popularity.
The aim of this study was to describe early patterns of tetrahydrocannabinol (THC) and cannabidiol (CBD) use in Florida following passage of the state's first medical marijuana law. We describe here the perceived benefits, side effects, and beliefs expressed by patients in a single outpatient academic palliative medicine practice.
A cross-sectional survey was performed of a sequential convenience sample of patients who presented to an outpatient academic palliative medicine clinic over a 3-month period.
In all, 24% (14/58) of respondents reported THC use, with half using THC on a daily basis. Patients reported improvements in pain, appetite, and nausea. In all, 71% (10/14) began using THC after the diagnosis of their chronic illness, and the most common form of usage was vaping. In all, 24% (14/58) of patients reported CBD use. Patients reported improvements in pain, and the most common form of usage was topical application. None of the patients had used CBD prior to the onset of their chronic illness. In all, 21% (3/14) of THC users and 21% (3/14) of CBD users thought that their substance was helping to cure their illness. Individual reported side effects in both groups were minimal.
Approximately a quarter of outpatient palliative care patients use THC or CBD, often on a daily basis. Palliative care providers should be aware of the frequency, diverse usage, and beliefs behind cannabis product use in this patient population.
在大麻类产品日益普及的情况下，姑息治疗医师面临着缺乏关于其疗效和剂量的指导的挑战。
本研究旨在描述在佛罗里达州通过首个医用大麻法后，大麻类产品中四氢大麻酚（THC）和大麻二酚（CBD）的早期使用模式。我们在此描述了在单一的门诊姑息治疗学术实践中，患者所表达的对这些产品的益处、副作用和看法。
对在 3 个月期间到门诊姑息治疗诊所就诊的连续便利样本患者进行了横断面调查。
共有 24%（14/58）的受访者报告使用了 THC，其中一半人每天都使用 THC。患者报告疼痛、食欲和恶心症状有所改善。在所有使用 THC 的患者中，有 71%（10/14）是在诊断出慢性疾病后开始使用的，最常见的使用形式是蒸气吸入。共有 24%（58/240）的患者报告使用了 CBD。患者报告疼痛有所改善，最常见的使用形式是局部应用。在所有使用 CBD 的患者中，没有一个人是在慢性疾病发病前开始使用的。在所有 THC 用户中，有 21%（3/14）和 CBD 用户中，有 21%（3/14）认为他们使用的物质有助于治愈他们的疾病。两组患者报告的个体不良反应都很少。
大约四分之一的门诊姑息治疗患者使用 THC 或 CBD，通常每天都使用。姑息治疗提供者应该了解在这一患者群体中，大麻类产品的使用频率、多样化的使用方式和背后的信念。
