Ney Luke J, Hsu Chia Ming K, Nicholson Emma, Zuj Daniel V, Clark L, Kleim Birgit, Felmingham Kim L
School of Psychology, University of Tasmania , Hobart, Australia.
School of Psychological Sciences, University of Melbourne , Melbourne, Australia.
Behav Sleep Med. 2021 Mar-Apr;19(2):178-191. doi: 10.1080/15402002.2020.1722127. Epub 2020 Jan 27.
: PTSD is characterised by severe sleep disturbances, which is increasingly recognised to in many cases consist of similar symptomology to sleep disorders such as REM Behaviour Disorder (RBD). The present study aimed to investigate whether different aspects of sleep quality influence intrusive memory development and whether PTSD status moderates this relationship. : 34 PTSD, 52 trauma-exposed (TE) and 42 non-trauma exposed (NTE) participants completed an emotional memory task, where they viewed 60 images (20 positive, 20 negative and 20 neutral) and, two days later, reported how many intrusive memories they had of each valence category. Participants also completed three measures of sleep quality: the Pittsburgh Sleep Quality Index, the REM Behaviour Disorder Screening Questionnaire and total hours slept before each session. : The PTSD group reported poorer sleep quality than both TE and NTE groups on all three measures, and significantly more negative intrusive memories than the NTE group. Mediation analyses revealed that self-reported RBD symptomology before the second session mediated the relationship between PTSD status and intrusive memories. Follow-up moderation analyses revealed that self-reported RBD symptomology before the second session was only a significant predictor of intrusion in the PTSD group, though with a small effect size. : These findings suggest that RBD symptomology is an indicator of consolidation of intrusive memories in PTSD but not trauma-exposed or healthy participants, which supports the relevance of characterising RBD in PTSD.
创伤后应激障碍（PTSD）的特征是严重的睡眠障碍，在许多情况下，人们越来越认识到其症状与诸如快速眼动睡眠行为障碍（RBD）等睡眠障碍相似。本研究旨在调查睡眠质量的不同方面是否会影响侵入性记忆的形成，以及PTSD状态是否会调节这种关系。34名PTSD患者、52名有创伤暴露经历（TE）的参与者和42名无创伤暴露经历（NTE）的参与者完成了一项情绪记忆任务，他们观看了60张图片（20张积极的、20张消极的和20张中性的），两天后，报告他们对每个效价类别有多少侵入性记忆。参与者还完成了三项睡眠质量测量：匹兹堡睡眠质量指数、快速眼动睡眠行为障碍筛查问卷以及每次实验前的总睡眠时间。PTSD组在所有三项测量中报告的睡眠质量均比TE组和NTE组差，并且比NTE组有更多的消极侵入性记忆。中介分析表明，第二次实验前自我报告的RBD症状介导了PTSD状态与侵入性记忆之间的关系。后续的调节分析表明，第二次实验前自我报告的RBD症状仅在PTSD组中是侵入性记忆的显著预测因素，尽管效应量较小。这些发现表明，RBD症状是PTSD中侵入性记忆巩固的一个指标，但在有创伤暴露经历的参与者或健康参与者中并非如此，这支持了在PTSD中对RBD进行特征描述的相关性。
