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1
Successful bone marrow transplant for Fanconi's anaemia.范科尼贫血的成功骨髓移植
Br Med J. 1977 Feb 12;1(6058):420-2. doi: 10.1136/bmj.1.6058.420.
2
Bone marrow transplantation from an unrelated donor for Fanconi's anaemia: two unusual complications.来自无关供者的范可尼贫血骨髓移植：两种罕见并发症
Bone Marrow Transplant. 1987 Jun;2(1):99-102.
3
Fanconi's anemia treated by allogeneic marrow transplantation.通过异基因骨髓移植治疗范科尼贫血。
Blood. 1983 May;61(5):954-9.
4
Bone marrow transplantation for Fanconi's anaemia.范科尼贫血的骨髓移植
Baillieres Clin Haematol. 1989 Jan;2(1):153-62. doi: 10.1016/s0950-3536(89)80012-5.
5
[Bone marrow transplantation in Fanconi's anaemia (author's transl)].
Sangre (Barc). 1981;26(3):380-2.
6
Unrelated donor bone marrow transplantation for severe aplastic anaemia and Fanconi's anaemia.无关供者骨髓移植治疗重型再生障碍性贫血和范科尼贫血。
Bone Marrow Transplant. 1989 Dec;4 Suppl 4:126-8.
7
Successful bone marrow transplant for hypoplastic anaemia.再生障碍性贫血的成功骨髓移植
Nurs Times. 1977 Feb 17;73(7):233-5.
8
[Allogenic bone marrow transplantation for Fanconi's anemia with leukemic transformation from an HLA identical father].
Rinsho Ketsueki. 1995 Jun;36(6):615-20.
9
Successful second bone marrow transplant for Fanconi's anaemia following escalation of conditioning.
Br J Haematol. 1997 Sep;98(3):772-4. doi: 10.1046/j.1365-2141.1997.2493066.x.
10
Regression of androgen-related hepatic tumors in patients with Fanconi's anemia following marrow transplantation.
Transplantation. 1984 May;37(5):452-5. doi: 10.1097/00007890-198405000-00006.

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Effects of an inadvertent dose of cytarabine in a child with Fanconi's anemia: reducing medication errors.阿糖胞苷意外剂量对一名范可尼贫血患儿的影响：减少用药错误
Paediatr Drugs. 2002;4(3):205-8. doi: 10.2165/00128072-200204030-00007.
2
Bone marrow transplantation.骨髓移植
Arch Dis Child. 1980 Oct;55(10):750-2. doi: 10.1136/adc.55.10.750.
3
Displacement bone marrow transplantation for some inborn errors.
J Inherit Metab Dis. 1990;13(4):572-96. doi: 10.1007/BF01799514.

本文引用的文献

1
Standardization of lymphocyte transformation to phytohaemagglutinin.淋巴细胞对植物血凝素转化的标准化
Clin Exp Immunol. 1973 Jul;14(3):457-67.
2
Agar culture studies in 127 cases of untreated acute leukemia: the prognostic value of reclassification of leukemia according to in vitro growth characteristics.127例未经治疗的急性白血病的琼脂培养研究：根据体外生长特征对白血病重新分类的预后价值。
Blood. 1974 Jul;44(1):1-18.
3
Allogeneic marrow grafting for treatment of aplastic anemia.
Blood. 1974 Feb;43(2):157-80.
4
Plastic isolators for treatment of acute leukaemia patients under "germ-free" conditions.用于在“无菌”条件下治疗急性白血病患者的塑料隔离器。
Br Med J. 1975 Dec 6;4(5996):549-52. doi: 10.1136/bmj.4.5996.549.
5
Technique of bone marrow transplantation.骨髓移植技术。
Proc R Soc Med. 1975 Sep;68(9):580-2. doi: 10.1177/003591577506800920.
6
Standardisation of the mixed lymphocyte reaction.混合淋巴细胞反应的标准化
J Immunol Methods. 1976;10(4):367-78. doi: 10.1016/0022-1759(76)90031-4.

范科尼贫血的成功骨髓移植

Successful bone marrow transplant for Fanconi's anaemia.

作者信息

Barrett A J, Brigden W D, Hobbs J R, Hugh-Jones K, Humble J G, James D C, Retsas S, Rogers T R, Selwyn S, Sneath P, Watson J G

出版信息

Br Med J. 1977 Feb 12;1(6058):420-2. doi: 10.1136/bmj.1.6058.420.

DOI:10.1136/bmj.1.6058.420
PMID:319872
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1604837/
Abstract

A 15-year-old boy with Fanconi's anaemia, who required four units of blood each month, received a bone marrow graft from his 9-year-old brother, who has HLA identical and compatible on mixed lymphocyte reaction. Considerable immunosuppression was used and bacterial infection was prevented by vigorous decontamination in a Vickers-Trexler isolator. After the graft the patient's blood counts remained satisfactory for nine months, but it took six months before qualitative immune function was normal.

摘要

一名患有范科尼贫血的15岁男孩，每月需要4个单位的血液，接受了来自他9岁弟弟的骨髓移植，其弟弟的人类白细胞抗原（HLA）相同且在混合淋巴细胞反应中相匹配。使用了相当程度的免疫抑制措施，并在维克斯 - 特雷克斯勒隔离器中通过强力净化预防细菌感染。移植后，患者的血细胞计数在九个月内保持令人满意的水平，但定性免疫功能恢复正常则花了六个月时间。