在萨斯喀彻温省，1980 年至 2013 年期间，原住民和非原住民女性妊娠糖尿病的流行病学。第 1 部分：人群、方法和频率（1980 年至 2009 年）；DIP：ORRIIGENSS 项目的结果。
Epidemiology of Diabetes in Pregnancy Among First Nations and Non-First Nations Women in Saskatchewan, 1980‒2013. Part 1: Populations, Methodology and Frequencies (1980‒2009); Results From the DIP: ORRIIGENSS Project.
机构信息
Department of Medicine (Canadian Center for Health and Safety in Agriculture), University of Saskatchewan, Saskatoon, Saskatchewan, Canada; Department of Community Health and Epidemiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Department of Medicine (Canadian Center for Health and Safety in Agriculture), University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
出版信息
Can J Diabetes. 2020 Oct;44(7):597-604. doi: 10.1016/j.jcjd.2019.10.005. Epub 2019 Nov 1.
OBJECTIVES
Because of the immediate and long-term consequences of diabetes in pregnancy (DIP) for mother and child, we compared frequencies of gestational diabetes (GDM) and pre-GDM between First Nations (FN) and non-FN people in Saskatchewan from 1980 to 2009.
METHODS
Using Ministry of Health administrative databases, we conducted a retrospective cohort study of GDM and pre-GDM rates within all FN and non-FN pregnancies in Saskatchewan. Annual crude and 10-year age-adjusted incidence of GDM and pre-GDM were determined as were maternal age-specific rates of DIP.
RESULTS
De-identified data were obtained for 69,176 FN and 344,410 non-FN pregnancies. The crude annual incidence of GDM rose from 1.0% to 6.6% among FN and from 0.4% to 3.6% among non-FN between 1980 and 2009. The crude annual incidence of pre-GDM rose from 0.7% to 2.0% among FN and from 0.4% to 0.9% among non-FN over the same period. The 10-year age-standardized incidence of GDM increased from 3.53% in 1980-1989 to 8.37% in 2000-2009 for FN, and from 1.55% to 3.13% for non-FN. For pre-GDM, the corresponding increases were from 1.65% to 3.26% for FN and from 0.5% to 0.91% for non-FN. Both GDM and pre-GDM rates increased with increasing maternal age, reaching 10.9% and 8.0% of FN pregnancies, and 7.7% and 1.1% of non-FN pregnancies, respectively, for mothers >40 years old.
CONCLUSIONS
The proportion of pregnancies complicated by DIP increased steadily among FN and non-FN women in Saskatchewan in 1980‒2009, but the incidence of GDM and pre-GDM is 2- to 3-fold higher among FN.
目的
鉴于妊娠糖尿病（DIP）对母婴的近期和长期影响，我们比较了 1980 年至 2009 年期间萨斯喀彻温省第一民族（FN）和非第一民族人群的妊娠期糖尿病（GDM）和孕前糖尿病（pre-GDM）的发病率。
方法
我们利用卫生部行政数据库，对萨斯喀彻温省所有 FN 和非 FN 孕妇的 GDM 和 pre-GDM 发病率进行了回顾性队列研究。确定了 GDM 和 pre-GDM 的年度粗发病率和 10 年年龄调整发病率，以及特定年龄的 DIP 产妇发病率。
结果
获得了 69176 名 FN 和 344410 名非 FN 妊娠的匿名数据。1980 年至 2009 年，FN 组 GDM 的粗年发病率从 1.0%上升至 6.6%，而非 FN 组从 0.4%上升至 3.6%。同期 FN 组 pre-GDM 的粗年发病率从 0.7%上升至 2.0%，而非 FN 组从 0.4%上升至 0.9%。1980-1989 年至 2000-2009 年，FN 组 10 年年龄标准化 GDM 发病率从 3.53%增至 8.37%，而非 FN 组从 1.55%增至 3.13%。对于 pre-GDM，FN 组的相应增长率为 1.65%至 3.26%，而非 FN 组为 0.5%至 0.91%。GDM 和 pre-GDM 发生率均随产妇年龄增加而增加，FN 组≥40 岁产妇的 GDM 和 pre-GDM 发生率分别为 10.9%和 8.0%，而非 FN 组分别为 7.7%和 1.1%。
结论
1980 年至 2009 年期间，萨斯喀彻温省 FN 和非 FN 女性中 DIP 妊娠的比例稳步增加，但 FN 女性的 GDM 和 pre-GDM 发病率是 2-3 倍。
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