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一名14岁男孩,患有仅累及肺部的Goodpasture综合征,是什么引发了大量咯血?

What triggered massive hemoptysis in Goodpasture syndrome with isolated pulmonary involvement in a 14-year-old boy?

作者信息

Şişmanlar-Eyüboğlu Tuğba, Aslan Ayşe Tana, Gezgin-Yıldırım Deniz, Buyan Necla, Emeksiz Serhat, Kalkan Gökhan

机构信息

Department of Pediatric Pulmonology, Dr Sami Ulus Maternity and Children Research and Training Hospital; Departments of.

Department of Pediatric Pulmonology, Gazi University Faculty of Medicine, Ankara, Turkey.

出版信息

Turk J Pediatr. 2019;61(4):611-614. doi: 10.24953/turkjped.2019.04.022.

Abstract

Şişmanlar-Eyüboğlu T, Aslan AT, Gezgin-Yıldırım D, Buyan N, Emeksiz S, Kalkan G. What triggered massive hemoptysis in Goodpasture syndrome with isolated pulmonary involvement in a 14-year-old boy? Turk J Pediatr 2019; 61: 611-614. Goodpasture syndrome is a rare, autoimmune disease associated with the development of antibodies against a specific antigen both in glomerular basement membrane and alveolar basement membrane. It is very rare in childhood and its incidence is not known. Although the mechanism of the disease is the same in lung as in the kidney, sometimes it presents with involvement of only one organ. Pulmonary involvement may be lifethreatening in patients with massive hemoptysis. Herein we report a 14-yearold boy with isolated lung involvement. He had massive hemoptysis following bronchoscopy and recovered succesfully with treatment.

摘要

肥胖者-艾于博卢T、阿斯兰AT、盖兹金-耶尔德勒姆D、布扬N、埃梅克西兹S、卡尔坎G。是什么引发了一名14岁孤立性肺部受累的古德帕斯丘综合征男孩的大量咯血?《土耳其儿科学杂志》2019年;61: 611 - 614。古德帕斯丘综合征是一种罕见的自身免疫性疾病,与针对肾小球基底膜和肺泡基底膜中特定抗原的抗体产生有关。它在儿童期非常罕见,发病率未知。尽管该疾病在肺部和肾脏的机制相同,但有时仅表现为一个器官受累。对于大量咯血的患者,肺部受累可能危及生命。在此,我们报告一名14岁孤立性肺部受累的男孩。他在支气管镜检查后出现大量咯血,并经治疗成功康复。

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