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一种罕见疾病的不常见表现:一例无肾脏受累的抗肾小球基底膜病。

An uncommon presentation of a rare disease: A case of anti-glomerular basement membrane disease without renal involvement.

作者信息

Polman Jeremy, Panzarello Rory, Patel Pratik, Tati Vasudev

机构信息

Baton Rouge General Internal Medicine Residency Program, USA.

出版信息

Respir Med Case Rep. 2020 Nov 7;31:101282. doi: 10.1016/j.rmcr.2020.101282. eCollection 2020.

Abstract

Anti-glomerular basement membrane disease (anti-GBM) is a well-documented, small vessel vasculitis that is classically associated with glomerulonephritis and alveolitis [1]. However, regardless of clinical process, not every patient will present with a constellation of classically associated symptoms. Literature review demonstrates that early anti-GBM disease can present as glomerulonephritis without alveolitis [2,3]. In this case report, we describe the unique clinical course of a 26-year-old male who originally presented with hemoptysis and his subsequent clinical workup revealing anti-glomerular basement membrane disease without renal involvement.

摘要

抗肾小球基底膜病(anti-GBM)是一种有充分文献记载的小血管炎,典型表现为肾小球肾炎和肺泡炎[1]。然而,无论临床过程如何,并非每个患者都会出现一系列典型相关症状。文献综述表明,早期抗GBM病可表现为无肺泡炎的肾小球肾炎[2,3]。在本病例报告中,我们描述了一名26岁男性独特的临床病程,该患者最初表现为咯血,随后的临床检查发现患有无肾脏受累的抗肾小球基底膜病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5db5/7695918/7645745a6f60/gr1.jpg

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