Life Sciences, Charles River Associates, London, UK.
National Institute of Infectious Diseases "Prof. Dr. Matei Bals", University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania.
Expert Rev Vaccines. 2020 Feb;19(2):123-132. doi: 10.1080/14760584.2020.1717952. Epub 2020 Jan 28.
: Across Europe, immunization programs have brought immense benefits to the prevention of infectious diseases. The vaccines used are procured through a variety of models such as tenders and Pricing & Reimbursement. However, to date, the impact of the procurement method on the performance and sustainability of vaccination programs and on public health has received little attention.: Drawing on a review of the academic and policy literature, complemented by an interview program with stakeholders involved in the procurement of vaccines, the authors have documented the relationship between procurement method dynamics and the level of protection against vaccine-preventable diseases in Germany, Italy, Spain and Romania for, measles-containing vaccines, hexavalent and influenza vaccines.: Price-based tenders can contribute to vaccine supply issues, discourage the provision of value-added services supporting vaccination coverage and disincentives future R&D. Although it is observed that price-based tenders can intensify competition in the short term, there can be unintended consequences such as damage to long-term competition. As European countries are committed to strengthen their immunization programs, they should consider the implications of current vaccine procurement models on the vaccine ecosystem and on public health.
: 在整个欧洲，免疫规划通过招标和定价与报销等各种模式，为预防传染病带来了巨大的益处。然而，迄今为止，采购方法对疫苗接种规划的绩效和可持续性以及公共卫生的影响还没有得到太多关注。: 本文通过对学术和政策文献的回顾，并辅以对参与疫苗采购的利益相关者的访谈计划，作者记录了采购方法动态与德国、意大利、西班牙和罗马尼亚针对含麻疹疫苗、六价疫苗和流感疫苗的疫苗可预防疾病的保护水平之间的关系。: 基于价格的招标可能会导致疫苗供应问题，阻碍提供支持疫苗接种覆盖率的增值服务，并抑制未来的研发。虽然观察到基于价格的招标可以在短期内加剧竞争，但也可能产生意想不到的后果，例如损害长期竞争。随着欧洲国家致力于加强其免疫规划，它们应该考虑当前疫苗采购模式对疫苗生态系统和公共卫生的影响。
