优化津巴布韦城市中艾滋病毒感染者的差异化治疗模式:一项混合方法研究的结果。

Optimizing differentiated treatment models for people living with HIV in urban Zimbabwe: Findings from a mixed methods study.

机构信息

ICAP at Columbia University, New York, New York, United States of America.

Department of Epidemiology, Columbia University Mailman School of Public Health, New York, New York, United States of America.

出版信息

PLoS One. 2020 Jan 28;15(1):e0228148. doi: 10.1371/journal.pone.0228148. eCollection 2020.

Abstract

INTRODUCTION

Zimbabwe is scaling up HIV differentiated service delivery (DSD) to improve treatment outcomes and health system efficiencies. Shifting stable patients into less-intensive DSD models is a high priority in order to accommodate the large numbers of newly-diagnosed people living with HIV (PLHIV) needing treatment and to provide healthcare workers with the time and space needed to treat people with advanced HIV disease. DSD is also seen as a way to improve service quality and enhance retention in care. National guidelines support five differentiated antiretroviral treatment models (DART) for stable HIV-positive adults, but little is known about patient preferences, a critical element needed to guide DART scale-up and ensure person-centered care. We designed a mixed-methods study to explore treatment preferences of PLHIV in urban Zimbabwe.

METHODS

The study was conducted in Harare, and included 35 health care worker (HCW) key informant interviews (KII); 8 focus group discussions (FGD) with 54 PLHIV; a discrete choice experiment (DCE) in which 500 adult DART-eligible PLHIV selected their preferences for health facility (HF) vs. community location, individual vs. group meetings, provider cadre and attitude, clinic operation times, visit frequency, visit duration and cost to patient; and a survey with the 500 DCE participants exploring DART knowledge and preferences.

RESULTS

Patient preferences were consistent in the FGDs, DCE and survey. Participants strongly preferred respectful HCWs, HF-based services, individual DART models, and less costly services. Patients also preferred less frequent visits and shorter wait times. They were indifferent to variations in HCW cadre and distances from home to HF. These preferences were mostly homogenous, with only minor differences between male vs. female and older vs. younger patients. HCWs in the KII correctly characterized facility-based individual models as the one most favored by patients; HCWs also preferred this model, which they felt decongested HFs and reduced their workload.

CONCLUSIONS

DART-eligible PLHIV in Harare found it relatively easy to access HFs, and preferred attributes associated with facility-based individual models. Prioritizing these for scale-up in urban areas may be the most efficient way to sustain positive patient outcomes and increase health system performance.

摘要

简介

津巴布韦正在扩大艾滋病毒差异化服务提供(DSD),以改善治疗效果和提高卫生系统效率。将稳定的患者转移到不那么密集的 DSD 模式是当务之急,以容纳大量新诊断的艾滋病毒感染者(PLHIV)需要治疗,并为卫生保健工作者提供治疗晚期艾滋病毒疾病患者所需的时间和空间。DSD 也被视为提高服务质量和增强护理保留率的一种方式。国家指南支持五种差异化抗逆转录病毒治疗模式(DART)用于稳定的 HIV 阳性成年人,但对于患者偏好知之甚少,这是指导 DART 扩大规模和确保以人为本的护理的关键因素。我们设计了一项混合方法研究,以探索津巴布韦城市中 PLHIV 的治疗偏好。

方法

该研究在哈拉雷进行,包括 35 次卫生保健工作者(HCW)关键知情人访谈(KII);8 次与 54 名 PLHIV 进行的焦点小组讨论(FGD);500 名符合 DART 条件的成年 PLHIV 进行离散选择实验(DCE),以选择他们对医疗机构(HF)与社区地点、个人与团体会议、提供者干部和态度、诊所运营时间、就诊频率、就诊时间和患者成本的偏好;以及对 500 名 DCE 参与者进行的一项调查,以探索 DART 知识和偏好。

结果

FGD、DCE 和调查中的患者偏好是一致的。参与者强烈倾向于尊重 HCW、HF 为基础的服务、个人 DART 模式和成本较低的服务。患者还更喜欢减少就诊次数和缩短等待时间。他们对 HCW 干部和家庭到 HF 的距离的变化漠不关心。这些偏好主要是同质的,只有男性与女性和老年与年轻患者之间存在较小差异。KII 中的 HCW 正确地将基于 HF 的个人模式描述为患者最青睐的模式;HCW 也更喜欢这种模式,他们认为这种模式使 HF 不再拥挤,并减轻了他们的工作量。

结论

哈拉雷符合 DART 条件的 PLHIV 相对容易获得 HF,并且更喜欢与基于 HF 的个人模式相关的属性。在城市地区优先考虑这些因素可能是维持积极的患者结果和提高卫生系统绩效的最有效方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad41/6986745/ed32c680290e/pone.0228148.g001.jpg

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