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在患有腹裂的婴儿中，母亲自身乳汁的喂养量与从开始喂养到出院的时间缩短以及住院时间相关。

Mother's own milk dose is associated with decreased time from initiation of feedings to discharge and length of stay in infants with gastroschisis.

作者信息

Storm Andrew P, Bowker Rakhee M, Klonoski Samuel C, Iantorno Stephanie E, Shah Ami N, Pillai Srikumar, Bell Jonathan, Patel Aloka L

机构信息

Rush Medical College, Chicago, IL, 60612, USA.

Section of Neonatology, Department of Pediatrics, Rush University Medical Center, Chicago, IL, 60612, USA.

出版信息

J Perinatol. 2020 Aug;40(8):1222-1227. doi: 10.1038/s41372-020-0595-3. Epub 2020 Jan 28.

DOI:10.1038/s41372-020-0595-3
PMID:31992819
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7223788/
Abstract

OBJECTIVE

To determine if mother's own milk (MOM) dose after gastroschisis repair is associated with time from feeding initiation to discharge. Secondary outcomes included parenteral nutrition (PN) duration and length of stay (LOS).

STUDY DESIGN

Retrospective study of 44 infants with gastroschisis examined demographics, gastroschisis type, PN days, timing of nutrition milestones, feeding composition, and LOS.

RESULTS

MOM dose was significantly associated with shorter time to discharge from feeding initiation (adjusted hazard ratio [HR] for discharge per 10% increase in MOM dose, 1.111; 95% CI, 1.011-1.220, p = 0.029). MOM dose was also significantly associated with shorter LOS (adjusted HR for discharge per 10% increase in MOM dose, 1.130; 95% CI, 1.028-1.242, p = 0.011).

CONCLUSIONS

MOM dose was significantly associated with a decrease in time to discharge from feeding initiation and LOS in a dose-dependent manner. Mothers of gastroschisis patients should receive education and proactive lactation support to optimize MOM volume for feedings.

摘要

目的

确定腹裂修补术后母亲自身乳汁（MOM）的摄入量是否与开始喂养至出院的时间相关。次要结局包括肠外营养（PN）持续时间和住院时间（LOS）。

研究设计

对44例腹裂婴儿进行回顾性研究，调查人口统计学特征、腹裂类型、PN天数、营养里程碑时间、喂养组成和住院时间。

结果

MOM摄入量与开始喂养至出院的时间显著相关（MOM摄入量每增加10%，出院的调整风险比[HR]为1.111；95%可信区间[CI]，1.011 - 1.220，p = 0.029）。MOM摄入量也与住院时间显著相关（MOM摄入量每增加10%，出院的调整HR为1.130；95% CI，1.028 - 1.242，p = 0.011）。

结论

MOM摄入量与开始喂养至出院的时间减少以及住院时间显著相关，且呈剂量依赖性。腹裂患儿的母亲应接受教育并获得积极的泌乳支持，以优化喂养时的MOM量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9fe/7223788/679b6ca010c6/41372_2020_595_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9fe/7223788/d60f1e7f4888/41372_2020_595_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9fe/7223788/679b6ca010c6/41372_2020_595_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9fe/7223788/d60f1e7f4888/41372_2020_595_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9fe/7223788/679b6ca010c6/41372_2020_595_Fig2_HTML.jpg

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Supplementation of Mother's Own Milk with Donor Milk in Infants with Gastroschisis or Intestinal Atresia: A Retrospective Study.以捐赠母乳补充母亲母乳在患有先天性腹壁裂或肠闭锁的婴儿中的应用：一项回顾性研究。
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