Department of Neonatology, Hôpital de la Croix-Rousse, Hospices civils de Lyon, Lyon, France.
CarMen laboratory, INSERM, INRA, Claude Bernard University Lyon1, Pierre-Benite, France.
Acta Paediatr. 2022 Jun;111(6):1127-1133. doi: 10.1111/apa.16296. Epub 2022 Mar 5.
The aim of this paper was to review the role that donor human milk plays in caring for very low birth weight (VLBW) infants.
This review focussed on academic papers and background information published in English and French up to 8 August 2021.
Donor human milk provides a useful bridge to successful breastfeeding in hospitalised neonates and does not have a negative impact on the use of mother's own milk and breastfeeding rates at discharge. It helps to prevent key complications of prematurity, particularly necrotising enterocolitis up to 36 weeks of postmenstrual age, which is more common in infants fed formulas based on cows' milk. When it is carefully fortified, it supports the postnatal growth of the majority of very preterm infants. Well-organised, accessible human milk banks are required to cover the needs of hospitalised infants, and donor human milk must be prioritised for patients who derive the greatest health benefit from it. These include very preterm infants and those born at term, or near term, with surgical digestive malformations or congenital heart disease.
Safe, high-quality donor human milk, which is distributed by well-organised human milk banks, is essential for the most vulnerable hospitalised neonates.
本文旨在回顾供体人乳在照顾极低出生体重(VLBW)婴儿方面的作用。
本综述重点关注截至 2021 年 8 月 8 日以英语和法语发表的学术论文和背景信息。
供体人乳为住院新生儿成功母乳喂养提供了有益的桥梁,并且不会对使用母亲自己的母乳和出院时的母乳喂养率产生负面影响。它有助于预防早产儿的关键并发症,特别是在达到 36 周龄前的坏死性小肠结肠炎,这在基于牛乳的配方奶喂养的婴儿中更为常见。当它被精心强化时,它可以支持大多数极早产儿的产后生长。需要有组织、可及的人乳库来满足住院婴儿的需求,并且应该优先为从供体人乳中获益最大的患者提供供体人乳。这些患者包括非常早产的婴儿和那些在出生时或接近足月时患有外科消化系统畸形或先天性心脏病的婴儿。
安全、高质量的供体人乳,由组织良好的人乳库分配,是最脆弱的住院新生儿所必需的。