Shaikhain Talal A, Al-Husayni Faisal, Elder Kareem
Internal Medicine, National Guard Hospital, Jeddah, SAU.
Cureus. 2019 Dec 20;11(12):e6425. doi: 10.7759/cureus.6425.
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most prescribed medications globally. They act through inhibiting cyclooxygenase (COX)-1 and COX-2 enzymes. In contrast to other NSAIDs, anaphylaxis due to ibuprofen is quite rare, especially in adults. The management of anaphylaxis depends on early recognition of the symptoms, administering epinephrine, and avoidance of the causing allergen. Here, we report a case of a 23-year-old female who presented with anaphylactic shock after ingesting ibuprofen.
非甾体抗炎药(NSAIDs)是全球处方量最大的药物之一。它们通过抑制环氧化酶(COX)-1和COX-2发挥作用。与其他非甾体抗炎药不同,布洛芬引起的过敏反应相当罕见,尤其是在成年人中。过敏反应的处理取决于对症状的早期识别、给予肾上腺素以及避免接触过敏原。在此,我们报告一例23岁女性在服用布洛芬后出现过敏性休克的病例。