Kay Emily, Ben-Shoshan Moshe
Department of Paediatrics, Montreal Children's Hospital, McGill University Health Center, Montreal, Quebec, Canada.
BMJ Case Rep. 2013 Jan 14;2013:bcr2012007873. doi: 10.1136/bcr-2012-007873.
Non-steroidal anti-inflammatory (NSAIDs) drugs are a group of medications acting through cyclooxygenase (COX-1) and cyclooxygenase (COX-2) enzymes inhibition. Hypersensitivity reactions to NSAIDs, although not rare, are poorly characterised and often go undiagnosed especially in children. We present in this paper a case of ibuprofen anaphylaxis that exemplifies the challenges involved in diagnosis and management of hypersensitivity reactions to NSAIDs.
非甾体抗炎药（NSAIDs）是一类通过抑制环氧化酶（COX-1）和环氧化酶（COX-2）发挥作用的药物。对NSAIDs的过敏反应虽然并不罕见，但特征描述不足，且常常未被诊断出来，尤其是在儿童中。我们在本文中呈现了一例布洛芬过敏反应的病例，该病例体现了NSAIDs过敏反应诊断和管理中所涉及的挑战。
