Gitlin Michael, Malhi Gin S
Department of Psychiatry, Geffen School of Medicine at UCLA, Los Angeles, USA.
CADE Clinic, Department of Psychiatry, Royal North Shore Hospital, St Leonards, USA.
Int J Bipolar Disord. 2020 Jan 28;8(1):5. doi: 10.1186/s40345-019-0175-7.
The issue of categorical vs. dimensional classification of bipolar disorder continues to generate controversy as it has for generations. Despite the evidence that no psychiatric disorder has discrete boundaries separating pathological and nonpathological states, and within a disorder, no clear differences separate subtypes-which would suggest a more dimensional approach-there are valid reasons to continue with our current categorical system, which distinguishes bipolar I from bipolar II disorder. Complicating the issue, a number of interested constituencies, including patients and their families, clinicians, scientists/researchers, and governmental agencies and insurance companies have different interests and needs in this controversy. This paper reviews both the advantages and disadvantages of continuing the bipolar I/bipolar II split vs. redefining bipolar disorder as one unified diagnosis. Even with one unified diagnosis, other aspects of psychopathology can be used to further describe and classify the disorder. These include both predominant polarity and categorizing symptoms by ACE-activity, cognition and energy. As a field, we must decide whether changing our current classification before we have a defining biology and genetic profile of bipolar disorder is worth the disruption in our current diagnostic system.
双相情感障碍的分类诊断究竟是采用类别法还是维度法,这一问题世世代代以来一直备受争议。尽管有证据表明,没有哪种精神障碍存在区分病理状态和非病理状态的明确界限,而且在一种障碍内部,各亚型之间也没有明显差异——这表明或许应采用更具维度性的方法——但仍有合理的理由沿用我们目前的分类系统,即区分双相I型障碍和双相II型障碍。使问题更加复杂的是,包括患者及其家属、临床医生、科学家/研究人员以及政府机构和保险公司在内的一些相关群体,在这场争论中有着不同的利益和需求。本文回顾了继续区分双相I型/双相II型与将双相情感障碍重新定义为单一统一诊断的利弊。即便采用单一统一诊断,精神病理学的其他方面仍可用于进一步描述和分类该障碍。这些方面包括主要的极性以及根据ACE活动、认知和精力对症状进行分类。作为一个领域,我们必须决定,在尚未明确双相情感障碍的生物学特征和基因图谱之前,改变我们目前的分类方式是否值得扰乱我们现有的诊断系统。