Lima Maria do Carmo Pinto, Melo Adriana Suely Oliveira, Sena Aline Silva Santos, Barros Vivianne de Oliveira, Amorim Melania Maria Ramos
. Instituto Paraibano de Pesquisa Joaquim Amorim Neto (IPESQ), Campina Grande, PB, Brasil.
. Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, PE, Brasil.
Rev Assoc Med Bras (1992). 2019 Dec;65(12):1489-1495. doi: 10.1590/1806-9282.65.12.1489.
Evaluate the prevalence of metabolic syndrome (MS) and the main associated maternal factors in women without pre-gestational conditions, in early pregnancy and in the immediate postpartum.
Two hundred pregnant women were evaluated at the 16th week of pregnancy, and 187 were reassessed postpartum. MS was diagnosed according to the criteria by the National Cholesterol Education Program Adult Treatment Panel III. In addition to the diagnostic criteria, anthropometric measures, blood pressure, metabolic profile, and visceral and subcutaneous fat thickness (by ultrasonography) were collected from the pregnant woman. The student's t-test was used to compare the prevalence of MS and its components in the 16th week and in the postpartum. Multiple logistic regression was performed to identify the principal factors associated with the syndrome.
The prevalence of the MS was 3.0% in early pregnancy and 9.7% postpartum (p=0.01). Following multiple logistic regression, the prepregnancy body mass index (BMI) (p=0.04) and high-density lipoprotein cholesterol (HDL-c) (p=0.02) remained associated with MS at 16 weeks, and triglyceride levels evaluated in postpartum (p<0.001) with MS in postpartum.
The frequency of the MS was high in the immediate postpartum. The factors associated were prepregnancy BMI and HDL-c at the 16th week, as well as triglyceride levels postpartum.
评估孕前无基础疾病的女性在孕早期及产后即刻代谢综合征（MS）的患病率及其主要相关母体因素。
对200名孕妇在妊娠第16周进行评估，187名孕妇在产后进行重新评估。根据美国国家胆固醇教育计划成人治疗专家组III的标准诊断MS。除诊断标准外，还收集了孕妇的人体测量指标、血压、代谢谱以及内脏和皮下脂肪厚度（通过超声检查）。采用学生t检验比较妊娠第16周和产后MS及其组分的患病率。进行多因素logistic回归分析以确定与该综合征相关的主要因素。
孕早期MS患病率为3.0%，产后为9.7%（p = 0.01）。多因素logistic回归分析显示，孕前体重指数（BMI）（p = 0.04）和高密度脂蛋白胆固醇（HDL-c）（p = 0.02）在妊娠第16周时仍与MS相关，产后甘油三酯水平（p < 0.001）与产后MS相关。
产后即刻MS的发生率较高。相关因素为妊娠第16周时的孕前BMI和HDL-c，以及产后甘油三酯水平。
