巴西玛瑙斯市成年人巨细胞病毒及其与 Epstein-Barr 病毒共同感染的血清流行率：一项基于人群的研究。
Seroprevalence of cytomegalovirus and its coinfection with Epstein-Barr virus in adult residents from Manaus: a population-based study.
机构信息
Universidade Estadual de Campinas, Faculdade de Ciências Farmacêuticas, Campinas, SP, Brasil.
Instituto Nacional de Pesquisas da Amazônia, Manaus, AM, Brasil.
出版信息
Rev Soc Bras Med Trop. 2020 Jan 27;53:e20190363. doi: 10.1590/0037-8682-0363-2019. eCollection 2020.
INTRODUCTION
This study assessed the seroprevalence of cytomegalovirus, associated factors, and Epstein-Barr virus coinfection among adult residents of Manaus.
METHODS
Using a cross-sectional study design, we collected blood samples from 136 individuals in a household survey in 2016. Prevalence ratios were calculated using Poisson regression.
RESULTS
Cytomegalovirus and Epstein-Barr virus seroprevalences were 67.6% (95% CI: 9.7-75.6%) and 97.8% (95% CI: 95.3-100.0%), respectively. Coinfection was observed in 66.2% (95% CI: 58.1-74.2%) of participants. Bivariate analysis showed no statistical association.
CONCLUSIONS
Seroprevalences were high among participants and approximately 7 out of 10 individuals had cytomegalovirus and Epstein-Barr virus coinfection.
简介
本研究评估了玛瑙斯成年居民的巨细胞病毒血清流行率、相关因素和 Epstein-Barr 病毒合并感染。
方法
采用横断面研究设计，我们于 2016 年在家庭调查中收集了 136 名个体的血液样本。使用泊松回归计算患病率比。
结果
巨细胞病毒和 Epstein-Barr 病毒的血清流行率分别为 67.6%（95%CI：9.7-75.6%）和 97.8%（95%CI：95.3-100.0%）。66.2%（95%CI：58.1-74.2%）的参与者观察到合并感染。二变量分析显示无统计学关联。
结论
参与者的血清流行率较高，约 10 人中就有 7 人同时感染巨细胞病毒和 Epstein-Barr 病毒。
Zotero 插件