Kharouba Johny, Somri Mostafa, Hadjittofi Christopher, Hasan Jomana, Blumer Sigalit
J Clin Pediatr Dent. 2020;44(1):60-65. doi: 10.17796/1053-4625-44.1.11.
: Sedation using 50% nitrous oxide (NO) concentration is common in pediatric dentistry. The aim to assess sedation and cooperation levels following sedation with 60% and 70% NO concentrations in children whose dental treatment failed using 50% NO concentration. : Children (n=51) aged 5-10 years were included. Sedation started with NO concentration of 50%; when appropriate cooperation and sedation were not achieved, NO concentration was increased to 60%, and subsequently to 70% during the same session. Sedation and cooperation levels were the primary outcomes. Adverse events were defined as secondary outcomes. At 50% NO concentration, five children reached adequate sedation and cooperation and completed their dental treatment, where 32 children completed the treatment at 60% NO concentration. Fourteen children required a concentration of 70% to complete treatment. For ten of the latter, treatment was successfully completed, while for four, treatment failed, despite the achievement of adequate sedation. Adverse events were observed in 9%, 22%, of the children who received 60%, 70% NO concentrations, respectively. When sedation with 50% NO concentration does not achieve satisfactory cooperation to complete pediatric dental treatment, 60% NO concentration appears to be more effective than 50% and safer than 70%.
在儿童牙科中，使用50%氧化亚氮（NO）浓度进行镇静是常见的。目的是评估在使用50%NO浓度镇静牙科治疗失败的儿童中，使用60%和70%NO浓度镇静后的镇静和合作水平。纳入5-10岁儿童（n=51）。镇静从50%的NO浓度开始；当未达到适当的合作和镇静效果时，NO浓度在同一次治疗中提高到60%，随后提高到70%。镇静和合作水平是主要结局。不良事件被定义为次要结局。在50%NO浓度时，5名儿童达到了足够的镇静和合作并完成了牙科治疗，32名儿童在60%NO浓度时完成了治疗。14名儿童需要70%的浓度才能完成治疗。对于其中10名儿童，治疗成功完成，而对于4名儿童，尽管达到了足够的镇静，但治疗仍失败。分别在接受60%、70%NO浓度的儿童中，不良事件发生率为9%、22%。当使用50%NO浓度镇静不能获得令人满意的合作以完成儿童牙科治疗时，60%NO浓度似乎比50%更有效且比70%更安全。
