Yasui-Furukori Norio, Murakami Hiroshi, Otaka Hideyuki, Tanabe Jutaro, Yanagimachi Miyuki, Murabayashi Masaya, Matsumura Koki, Matsuhashi Yuki, Nakayama Hirofumi, Mizushiri Satoru, Sugawara Norio, Daimon Makoto, Shimoda Kazutaka
Department of Psychiatry, Dokkyo Medical University School of Medicine, Mibu, Shimotuga, Tochigi, Japan.
Department of Neuropsychiaty, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Psychiatry Investig. 2020 Jan;17(1):78-84. doi: 10.30773/pi.2019.0210. Epub 2020 Jan 25.
Glycemic control varies based on lifestyle factors and stress coping mechanisms, which are influenced by personality. The psychological factors associated with glycemic control have not yet been established in patients with type 2 diabetes mellitus (T2DM). The relationship between a 5-factor model of personality and glycemic control was evaluated in individuals with T2DM.
The subjects were 503 Japanese outpatients with T2DM. Glycated hemoglobin A1c (HbA1c) levels, depressive status, insomnia and personality traits were assessed. Lifestyle factors of the patients, such as habitual alcohol consumption and smoking, were also included in the analyses.
Because the influence of insulin therapy on HbA1c is so strong, we stratified the patients according to insulin use. Simple regression analysis showed a significant correlation between HbA1c and neuroticism in patients who did not use insulin. After adjustment for confounders, multiple regression analyses revealed that none of the personality factors, including neuroticism, were found to be associated with HbA1c.
These findings suggest that personality traits do not have a large impact on glycemic control. Further studies are required to confirm the relationships between psychological factors and glycemic control using a longitudinal study design.
血糖控制因生活方式因素和应激应对机制而异,而这些又受人格的影响。2型糖尿病(T2DM)患者中与血糖控制相关的心理因素尚未明确。本研究评估了T2DM患者人格五因素模型与血糖控制之间的关系。
研究对象为503名日本T2DM门诊患者。评估糖化血红蛋白A1c(HbA1c)水平、抑郁状态、失眠及人格特质。患者的生活方式因素,如习惯性饮酒和吸烟,也纳入分析。
由于胰岛素治疗对HbA1c的影响非常大,我们根据胰岛素使用情况对患者进行分层。简单回归分析显示,未使用胰岛素的患者中,HbA1c与神经质之间存在显著相关性。在对混杂因素进行调整后,多元回归分析显示,包括神经质在内的人格因素均未发现与HbA1c相关。
这些发现表明人格特质对血糖控制影响不大。需要进一步研究采用纵向研究设计来证实心理因素与血糖控制之间的关系。