Department of Psychiatry & Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA.
Graduate Program in Physical Education, Catholic University of Brasilia, Brasilia, Brazil.
AIDS Care. 2021 Mar;33(3):368-374. doi: 10.1080/09540121.2020.1719278. Epub 2020 Jan 29.
HIV is a worldwide public health issue affecting millions of individuals, and people living with HIV (PLWH) are often affected by depression. Nonetheless, exercise can prevent and treat depression among PLWH. The aim of the present study was to investigate the effect of exercise on depression symptoms in PLWH. Using a prospective single-arm trial, a semi-supervised community-based exercise intervention was offered 3 times/week for 12 weeks to PLWH (n = 52; age: 49 ± 6 years; HIV diagnosis: 19 ± 15 years). Participants were divided into compliant (≥1 exercise session/week) and non-compliant (<1 exercise session/week) groups according to their attendance in the intervention. Depression symptoms were assessed using the Beck Depression Inventory (BDI), and the change in BDI from baseline to post-intervention was assessed with an analysis of covariance, adjusted for demographics. The post-intervention BDI score was significantly lower (p = 0.027) for the compliant group compared to the non-compliant group, and the rate of improvement from moderate/severe symptoms of depression to minimal symptoms of depression was four times greater in the compliant group. In conclusion, a community-based exercise program may be effective in reducing depression symptoms among PLWH.
艾滋病毒是一个影响全球数百万人的公共卫生问题，艾滋病毒感染者（PLWH）经常受到抑郁的影响。然而，运动可以预防和治疗 PLWH 的抑郁。本研究旨在探讨运动对 PLWH 抑郁症状的影响。采用前瞻性单臂试验，对 52 名 PLWH（年龄：49±6 岁；HIV 诊断：19±15 年）每周进行 3 次、为期 12 周的半监督社区为基础的运动干预。参与者根据他们在干预中的出勤情况分为依从组（≥1 次运动/周）和不依从组（<1 次运动/周）。采用贝克抑郁量表（BDI）评估抑郁症状，并用协方差分析评估从基线到干预后的 BDI 变化，调整人口统计学因素。与不依从组相比，依从组的干预后 BDI 评分显著降低（p=0.027），并且依从组从中度/重度抑郁症状改善到轻度抑郁症状的比例是不依从组的四倍。总之，基于社区的运动方案可能对降低 PLWH 的抑郁症状有效。
