Bogatyrev I V, Vakhliaev V D, Makolkin V I, Syrkin A L
Kardiologiia. 1988 Aug;28(8):52-5.
Changes in the rate of coronary venous flow through the affected area under the effect of intravenous jet injections of propranolol, 0.1 mg per 1 kg body weight, were assessed in 18 patients of the hyperkinetic central hemodynamic type during acute myocardial infarction. In the first group of patients, whose mean flow rate through the affected wall was 106.2 +/- 5.7 ml/min, the latter parameter decreased in proportion to the drop in double product. In the second group of patients, whose coronary venous flow rate was reduced (51.4 +/- 6.9 ml/min), propranolol-induced drop in the flow rate was less marked, as compared to the drop in double product. It was correlated with dramatically depressed pumping function of the heart.
对18例急性心肌梗死时处于高动力性中心血流动力学类型的患者，评估静脉注射每1公斤体重0.1毫克普萘洛尔后，通过梗死区域的冠状静脉血流速率的变化。在第一组患者中，通过梗死壁的平均血流速率为106.2±5.7毫升/分钟，该参数随双乘积的下降成比例降低。在第二组患者中，其冠状静脉血流速率降低（51.4±6.9毫升/分钟），与双乘积的下降相比，普萘洛尔引起的血流速率下降不太明显。这与心脏泵血功能的显著降低相关。
