National Hospital of Traditional Medicine, Hanoi, Vietnam.
National Hospital of Obstetrics and Gynecology, Hanoi, Vietnam.
Adv Ther. 2020 Mar;37(3):1136-1144. doi: 10.1007/s12325-020-01238-9. Epub 2020 Jan 29.
Doppler-guided transanal hemorrhoidal dearterialization (THD) was considered a less invasive and innovative method to treat hemorrhoidal disease, but it may impact the anal area during dearterialization and mucopexy. Thus, this study aimed to assess any changes in anorectal manometry of grade III and IV hemorrhoidal patients following THD treatment.
This prospective observational study was conducted with patients who had grades III and IV hemorrhoidal disease. The patients were treated using THD at the Department of Surgery in the National Hospital of Traditional Medicine (Hanoi, Vietnam) between June 2012 and December 2013. Anorectal manometry was performed prior to THD and again between 6 and 12 months following the procedure.
A total of 40 patients were enrolled in the study, including 32 with grade III hemorrhoids and 8 with grade IV hemorrhoids. The proportion of male patients (65%) was higher than that of female patients (35%), and the majority of patients (82.5%) were > 40 years old. The mean duration of symptoms prior to treatment was 12.3 years. The mean length of the anal sphincter was unchanged before and after THD (3.64 ± 0.40 cm prior to treatment vs. 3.66 ± 0.48 cm following treatment; p = 0.57). Significant differences in treatment-related changes were detected for all anorectal manometric measurements except maximum squeezing pressure (p < 0.05). No patient showed anal stenosis or fecal incontinence.
The THD technique did not change the length of the anal sphincter 6 months after hemorrhoid treatment. The values of anal pressure and rectal sensation decreased almost significantly between treatment and the follow-up visit. We suggest that further studies, which include larger sample sizes, should be conducted to confirm THD effectiveness in terms of anorectal functions.
多普勒引导下经肛门直肠动脉结扎术(THD)被认为是一种治疗痔病的微创且有创新性的方法,但在动脉结扎和黏膜固定术中可能会对肛门区域产生影响。因此,本研究旨在评估 THD 治疗后 III 级和 IV 级痔患者的肛门直肠测压的任何变化。
这是一项前瞻性观察研究,纳入了在越南国家传统医学医院(河内)外科接受 THD 治疗的 III 级和 IV 级痔患者。在 THD 治疗前和治疗后 6 至 12 个月进行肛门直肠测压。
共有 40 例患者入组研究,其中 32 例为 III 级痔,8 例为 IV 级痔。男性患者(65%)的比例高于女性患者(35%),大多数患者(82.5%)年龄>40 岁。治疗前症状的平均持续时间为 12.3 年。THD 前后肛门括约肌的平均长度无变化(治疗前 3.64±0.40cm,治疗后 3.66±0.48cm;p=0.57)。除最大收缩压外(p<0.05),所有肛门直肠测压测量的治疗相关变化均有显著差异。无患者出现肛门狭窄或大便失禁。
THD 技术不会改变痔治疗 6 个月后肛门括约肌的长度。治疗和随访时肛门压力和直肠感觉值几乎显著下降。我们建议进一步的研究,包括更大的样本量,以确认 THD 在肛门直肠功能方面的有效性。