急性运动对环境引起的干眼症症状的影响。
The effect of acute exercise on environmentally induced symptoms of dry eye.
机构信息
Department of Sport, Exercise and Rehabilitation, Northumbria University, Newcastle-upon-Tyne, United Kingdom.
Department of Applied Sciences, Northumbria University, Newcastle-upon-Tyne, United Kingdom.
出版信息
Physiol Rep. 2020 Jan;8(2):e14262. doi: 10.14814/phy2.14262.
The purpose of this study was to investigate the effects of acute exercise on environmentally induced symptoms of dry eye. Twelve participants without dry eye disease volunteered to complete three experimental visits in a randomized order; (1) control condition seated for 1 h at a relative humidity (RH) of 40% (CONT), (2) dry condition seated for 1 h at a RH of 20% (DRY), and (3) exercise condition seated for 40 min followed by 20 min of cycling exercise at a RH of 20% (EXER). Tear volume, tear matrix metalloproteinase 9 (MMP-9), perception of dry eye symptoms (frequency and severity), core temperature, and ocular surface temperature (OST) were measured at the end of each exposure. The perception of dry eye frequency and MMP-9 concentration were significantly higher in DRY compared to CONT (P < 0.012), with no differences in EXER compared to CONT. The results suggest that an acute bout of exercise may attenuate symptoms of environmentally induced dry eye, and warrant further research.
本研究旨在探讨急性运动对环境引起的干眼症症状的影响。12 名没有干眼症的参与者自愿以随机顺序完成三次实验访问；（1）在相对湿度（RH）为 40%的情况下静坐 1 小时（CONT），（2）在 RH 为 20%的情况下静坐 1 小时（DRY），（3）在 RH 为 20%的情况下静坐 40 分钟，然后进行 20 分钟的自行车运动（EXER）。在每次暴露结束时测量泪液体积、泪液基质金属蛋白酶 9（MMP-9）、干眼症状的感知（频率和严重程度）、核心温度和眼表面温度（OST）。与 CONT 相比，DRY 时干眼症状的频率和 MMP-9 浓度显著升高（P<0.012），而与 CONT 相比，EXER 时无差异。结果表明，急性运动可能会减轻环境引起的干眼症症状，值得进一步研究。
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