Garand Kendrea L Focht, Culp Lindsey, Wang Bin, Davidson Kate, Martin-Harris Bonnie
Department of Speech Pathology and Audiology, University of South Alabama, Mobile, AL, USA.
Department of Mathematics and Statistics, University of South Alabama, Mobile, AL, USA.
Ann Otol Rhinol Laryngol. 2020 Jun;129(6):618-624. doi: 10.1177/0003489420903332. Epub 2020 Jan 30.
The purpose of this study was to examine age-related effects on esophageal transit times (ETT) among healthy adult participants.
A total of 175 healthy, non-dysphagic participants underwent a modified barium swallow study (MBSS), and ETT was recorded for two standardized swallowing tasks. Differences across age groups were determined using Kruskal-Wallis test. Relationships between an Esophageal Clearance (Modified Barium Swallow Impairment Profile Component 17) score and ETT were also explored.
No significant differences were observed in ETT across age groups for nectar-thickened liquid ( = .335) or pudding ( = .231) consistencies. No significant differences were observed between males and females in ETT for either the nectar ( = .112) or pudding trial ( = .817). For nectar, the mean ETT for patients with Component 17 scores of 2 or greater were significantly higher than that of participants with a score of 0 ( < .0001). For pudding, participants with a score >0 demonstrated significantly higher mean ETT compared to participants with a score of 0 (with = .0008 and < .0001, respectively).
Study findings failed to support age-related or sex-related differences in ETT for two standardized swallowing tasks administered during a MBSS in healthy individuals. The normative values following a standardized protocol in this study provide guidance in clinical interpretation of esophageal function.
本研究旨在探讨健康成年参与者中年龄对食管通过时间（ETT）的影响。
共有175名健康、无吞咽困难的参与者接受了改良钡餐吞咽研究（MBSS），并记录了两项标准化吞咽任务的ETT。使用Kruskal-Wallis检验确定各年龄组之间的差异。还探讨了食管清除率（改良钡餐吞咽障碍概况组件17）评分与ETT之间的关系。
对于花蜜状浓稠液体（=0.335）或布丁（=0.231）的稠度，各年龄组的ETT未观察到显著差异。在花蜜状（=0.112）或布丁试验（=0.817）中，男性和女性的ETT也未观察到显著差异。对于花蜜状物质，组件17评分≥2的患者的平均ETT显著高于评分为0的参与者（<0.0001）。对于布丁，评分>0的参与者的平均ETT显著高于评分为0的参与者（分别为=0.0008和<0.0001）。
研究结果未能支持在健康个体的MBSS期间进行的两项标准化吞咽任务中，ETT存在与年龄或性别相关的差异。本研究中遵循标准化方案的标准值为食管功能的临床解释提供了指导。
