Postgraduate Program in Health Sciences, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Medical College of the Federal University of Sergipe, Department of Medicine, Aracaju, Sergipe, Brazil.
PLoS One. 2020 Jan 30;15(1):e0228176. doi: 10.1371/journal.pone.0228176. eCollection 2020.
Visceral leishmaniasis (VL) is a severe, systemic and potentially lethal parasitosis. The lung, like any other organ, can be affected in VL, and interstitial pneumonitis has been described in past decades. This research aimed to bring more recent knowledge about respiratory impairment in VL, characterizing pulmonary involvement through clinical, radiographic and tomographic evaluation. This is an observational, cross-sectional study that underwent clinical evaluation, radiography and high-resolution computed tomography of the chest in patients admitted with the diagnosis of VL in a university service in Northeast Brazil, from January 2015 to July 2018. The sample consisted of 42 patients. Computed tomography was considered abnormal in 59% of patients. Images compatible with pulmonary interstitial involvement were predominant (50%). The most observed respiratory symptom was cough (33.3%), followed by tachypnea (14.1%). Chest radiography was altered in only four patients. VL is a disease characterized by systemic involvement and broad spectrum of clinical manifestations. The respiratory symptoms and tomographic alterations found show that the involvement of respiratory system in VL deserves attention because it is more common than previously thought. Chest X-ray may not reveal this impairment.
内脏利什曼病(VL)是一种严重的、全身性的、潜在致命的寄生虫病。肺像任何其他器官一样,可能会受到 VL 的影响,过去几十年中已经描述了间质性肺炎。本研究旨在提供 VL 中呼吸障碍的最新知识,通过临床、影像学和胸部计算机断层扫描来描述肺部受累情况。这是一项在巴西东北部一所大学附属医院进行的观察性、横断面研究,对 2015 年 1 月至 2018 年 7 月间诊断为 VL 的患者进行了临床评估、X 线摄影和高分辨率胸部计算机断层扫描。该样本包括 42 名患者。59%的患者计算机断层扫描异常。与肺间质受累相符的图像占主导地位(50%)。最常见的呼吸系统症状是咳嗽(33.3%),其次是呼吸急促(14.1%)。只有 4 名患者的 X 线胸片有改变。VL 是一种以全身受累和广泛的临床表现为特征的疾病。所发现的呼吸系统症状和断层扫描改变表明,VL 对呼吸系统的累及值得关注,因为它比以前认为的更为常见。胸部 X 光片可能无法显示这种损害。