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硝酸甘油在凶险性前置胎盘和胎盘植入且预计气道困难患者并行子宫横切口剖宫产术中的应用:一例病例报告及文献复习

Use of nitroglycerin for parallel transverse uterine cesarean section in patients with pernicious placenta previa and placenta accrete and predicted difficult airway: A case report and review of literature.

作者信息

Ma Yushan, You Yong, Jiang Xiaoqin, Lin Xuemei

机构信息

Department of Anesthesiology, West China Second University Hospital, Sichuan University.

Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education.

出版信息

Medicine (Baltimore). 2020 Jan;99(5):e18943. doi: 10.1097/MD.0000000000018943.

DOI:10.1097/MD.0000000000018943
PMID:32000415
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7004715/
Abstract

RATIONALE

The incidence of obstetric hemorrhage due to pernicious placenta previa (PPP) and placenta accreta is currently increasing in China. Parallel transverse uterine incision (PTUI) cesarean section (CS) is a novel technique designed to avoid transecting the placenta and control postpartum hemorrhage during CS in these patients in our hospital. A key point of anesthesia management related to PTUI CS involves keeping the uterus relaxed. General anesthesia (GA) has often been performed, and inhaled volatile anesthetics have traditionally been recommended for this purpose; however, GA may be contraindicated in patients with difficult airways.

PATIENT CONCERNS

The patient was predicted to have a difficult airway, and GA may have resulted in potentially life-threatening complications. An alternative and safer method of achieving uterine relaxation during PTUI CS was thus required.

DIAGNOSES

The patient was diagnosed with PPP, and a predicted difficult airway was suspected preoperatively.

INTERVENTIONS

PTUI CS was planned to control postpartum hemorrhage and preserve fertility during CS. Uterine relaxation during PTUI CS was achieved with intravenous nitroglycerin under combined spinal-epidural anesthesia.

OUTCOME

Intravenous nitroglycerin and combined spinal-epidural anesthesia achieved uterine relaxation during the time from delivery of the neonate to making the second transverse incision in the lower segment of the uterus during PTUI CS. Both the parturient and neonate were well and were discharged 4 days later.

LESSIONS

Intravenous nitroglycerin and combined spinal-epidural anesthesia may offer an alternative to GA for achieving uterine relaxation in patients with PPP and a predicted difficult airway undergoing PTUI CS to control postpartum hemorrhage.

摘要

理论依据

在中国,凶险性前置胎盘(PPP)和胎盘植入导致的产科出血发生率目前正在上升。平行横向子宫切口(PTUI)剖宫产术(CS)是我院设计的一种新技术,旨在避免切断胎盘并在这些患者剖宫产时控制产后出血。与PTUI剖宫产术相关的麻醉管理的一个关键点是保持子宫松弛。通常采用全身麻醉(GA),传统上推荐使用吸入性挥发性麻醉剂来达到这一目的;然而,GA在气道困难的患者中可能是禁忌的。

患者情况

该患者预计气道困难,全身麻醉可能会导致潜在的危及生命的并发症。因此,需要一种在PTUI剖宫产术中实现子宫松弛的替代且更安全的方法。

诊断

该患者被诊断为PPP,术前怀疑气道困难。

干预措施

计划进行PTUI剖宫产术以控制产后出血并在剖宫产时保留生育能力。在腰麻-硬膜外联合麻醉下,通过静脉注射硝酸甘油实现PTUI剖宫产术中子宫松弛。

结果

在PTUI剖宫产术从新生儿娩出到在子宫下段做第二个横向切口的过程中,静脉注射硝酸甘油和腰麻-硬膜外联合麻醉实现了子宫松弛。产妇和新生儿情况良好,4天后出院。

经验教训

对于患有PPP且预计气道困难、接受PTUI剖宫产术以控制产后出血的患者,静脉注射硝酸甘油和腰麻-硬膜外联合麻醉可能是全身麻醉实现子宫松弛的一种替代方法。

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本文引用的文献

1
Parallel transverse uterine incisions combined with cell salvage minimized bleeding in a patient with pernicious placenta previa and an unexplained decrease in hemoglobin after transfusion of allogeneic red blood cells: A case report.平行横向子宫切口联合血液回收技术减少了一例凶险性前置胎盘患者的出血,该患者在输注异体红细胞后血红蛋白出现不明原因下降:病例报告
Medicine (Baltimore). 2019 May;98(18):e15434. doi: 10.1097/MD.0000000000015434.
2
Transfusion Management of Obstetric Hemorrhage.产科出血的输血管理。
Transfus Med Rev. 2018 Oct;32(4):249-255. doi: 10.1016/j.tmrv.2018.05.003. Epub 2018 May 31.
3
Parallel transverse uterine incisions to control postpartum hemorrhage and preserve fertility during cesarean delivery for placenta previa and accreta.在前置胎盘和胎盘植入剖宫产术中采用平行横向子宫切口控制产后出血并保留生育能力。
Int J Gynaecol Obstet. 2016 Aug;134(2):221-2. doi: 10.1016/j.ijgo.2016.02.013. Epub 2016 May 7.
4
The effects of sequential use of oxytocin and sublingual nitroglycerin in the cases of retained placenta.缩宫素与舌下含服硝酸甘油序贯应用于胎盘滞留病例的效果
J Matern Fetal Neonatal Med. 2016 Oct;29(20):3254-9. doi: 10.3109/14767058.2015.1124264. Epub 2015 Dec 23.
5
Nitroglycerin for management of retained placenta.用于处理胎盘滞留的硝酸甘油
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6
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Blood. 2015 Apr 30;125(18):2759-70. doi: 10.1182/blood-2014-10-512608. Epub 2015 Mar 13.
7
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8
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9
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10
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