危重症患儿白蛋白水平对儿科重症监护病房住院时间和死亡率的影响
The Influence of Albumin Level in Critically Ill Children to Length of Stay and Mortality in Paediatric Intensive Care Unit.
作者信息
Yanni Gema Nazri, Lubis Munar, Ali Muhammad
机构信息
Department of Child Health, Universitas Sumatera Utara, Medan, Indonesia.
出版信息
Open Access Maced J Med Sci. 2019 Oct 14;7(20):3455-3458. doi: 10.3889/oamjms.2019.445. eCollection 2019 Oct 30.
BACKGROUND
The use of albumin in the critical care setting is a very controversial issue. Low serum albumin concentration in critical illness is associated with a poor outcome.
AIM
We aimed to evaluate the influence of albumin level in critically ill children to the length of stay and mortality in the Pediatric Intensive Care Unit (PICU) Haji Adam Malik General Hospital, Medan, Indonesia.
METHODS
The study used an observational method with a cross-sectional design. The population of the study was all patients with major postoperative surgery and critically ill that admitted to the PICU at Haji Adam Malik Hospital from the period of June 2008 to September 2008. The albumin level of the subjects was determined on the first day admitted.
RESULTS
The group with hypoalbuminemia (< 3 g/dL) was given albumin supplementation according to a protocol in the PICU. The group with hypoalbuminemia have an average length of stay 7.6 days (9.7%) and mortality of 12 subjects (36.4%). The group with normal albumin level have 4.7 days (5.0%) and mortality 13 subjects (37.1%). There was no significant effect of albumin level to mortality.
CONCLUSION
Albumin level did not affect the length of stay and mortality in PICU.
背景
在重症监护环境中使用白蛋白是一个极具争议的问题。危重病患者血清白蛋白浓度低与预后不良相关。
目的
我们旨在评估印度尼西亚棉兰哈芝亚当马利克综合医院儿科重症监护病房（PICU）中危重症患儿的白蛋白水平对住院时间和死亡率的影响。
方法
本研究采用横断面设计的观察性方法。研究人群为2008年6月至2008年9月期间入住哈芝亚当马利克医院PICU的所有重大术后手术患者和危重症患者。在入院第一天测定受试者的白蛋白水平。
结果
低白蛋白血症组（<3 g/dL）根据PICU的方案给予白蛋白补充。低白蛋白血症组的平均住院时间为7.6天（9.7%），12名患者死亡（36.4%）。白蛋白水平正常的组平均住院时间为4.7天（5.0%），13名患者死亡（37.1%）。白蛋白水平对死亡率没有显著影响。
结论
白蛋白水平不影响PICU的住院时间和死亡率。
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