Academic Unit of Radiology, University of Sheffield, Floor C, Royal Hallamshire Hospital, Glossop Road, Sheffield, S10 2JF, UK.
Neuroradiology. 2020 May;62(5):617-627. doi: 10.1007/s00234-020-02364-5.
The aim of this study is to provide normative data about the appearances and dimensions of the cavum septi pellucidi and vergae (CSPV) on in utero MR (iuMR) imaging in second and third trimester foetuses.
Two hundred normal foetuses (from a low-risk pregnancy, with normal ante-natal USS findings and no intracranial abnormality of iuMR) had iuMR imaging between 18 and 37 gestational weeks (gw). The anatomical features on those studies were compared with published atlases of post-mortem foetal brains. The length, width and volume of the CSPV were measured in all foetuses.
The anatomy of the CSPV and its relationship with the corpus callosum and the fornices on iuMR imaging was comparable with post-mortem data at all gestational ages studied. The length of the CSPV increased throughout pregnancy, whereas the width and volume of CSPV reached a maximum between 29 and 31 gw and then showed a reduction later in pregnancy.
The iuMR imaging features of the CSPV and its close anatomical relations closely correspond to post-mortem data. The CSPV was patent in all cases but we have shown that closure commences in the midpart of the third trimester and advances in a posterior to anterior direction.
本研究旨在提供中孕期和晚孕期胎儿透明隔腔和穹窿（CSPV）的磁共振成像（iuMR）表现和测量值的正常值范围。
200 例正常胎儿（来自低危妊娠，产前超声检查正常，无颅内异常）在 18 至 37 孕周行 iuMR 检查。将这些研究的解剖特征与已发表的胎儿大脑尸检图谱进行比较。所有胎儿均测量透明隔腔的长度、宽度和体积。
在所有研究的孕周，CSPV 的解剖结构及其与胼胝体和穹窿的关系在 iuMR 成像上与尸检数据具有可比性。CSPV 的长度在整个孕期逐渐增加，而 CSPV 的宽度和体积在 29 至 31 孕周达到最大值，随后在妊娠后期减小。
CSPV 的 iuMR 成像特征及其密切的解剖关系与尸检数据非常吻合。所有病例均显示 CSPV 是开放的，但我们已经表明，它从中孕期的中段开始闭合，并从前向后逐渐进展。
