School of Materials Science and Engineering, University of New South Wales, Sydney, 2052, Australia.
School of Materials Science and Engineering, School of Chemistry, Australian Centre for Nanomedicine, University of New South Wales, Sydney, 2052, Australia.
Macromol Rapid Commun. 2020 Mar;41(5):e1900555. doi: 10.1002/marc.201900555. Epub 2020 Jan 31.
Structured color in nature is controlled by nano- and micro-structured interfaces giving rise to a photonic bandgap. This study presents a biomimetic optical material based on polymeric inverse opals that respond to enzyme activity. Polymer colloids provide a template in which acryloyl-functionalized poly(ethylene glycol) is integrated; dissolution of the colloids leads to a hydrogel inverse opal that can be lithographically patterned using transfer printing. Incorporating enzyme substrates within the voids provides a material that responds to the presence of proteases through a shift in the optical properties.
自然界中的结构色是由纳米和微结构界面控制的，这些界面产生光子带隙。本研究提出了一种基于聚合物反蛋白石的仿生光学材料，该材料对酶活性有响应。聚合物胶体提供了一个模板，其中整合了丙烯酰基功能化的聚（乙二醇）；胶体的溶解导致水凝胶反蛋白石的形成，该反蛋白石可以使用转印印刷进行光刻图案化。在空隙中加入酶底物可以得到一种材料，该材料通过光学性质的变化对蛋白酶的存在做出响应。
