Vinters H V, Guerra W F, Eppolito L, Keith P E
Department of Pathology, UCLA Medical Center 90024-1732.
Neuropathol Appl Neurobiol. 1988 Sep-Oct;14(5):417-24. doi: 10.1111/j.1365-2990.1988.tb01142.x.
A patient with AIDS-related complex (ARC) presented with a fulminant neurologic syndrome suggestive of ascending myelopathy, and died approximately 48 h after admission to hospital. At necropsy, there was evidence of a severe necrotizing vasculitis affecting the nervous system most severely, with multifocal haemorrhagic necroses of the spinal cord and cauda equina. Although a rare intranuclear inclusion suggestive of herpesvirus infection was seen in the predominantly lympho-histiocytic infiltrate in and around blood vessel walls, the precise aetiology of the angiitis was not apparent. It may represent a response to AIDS virus infection of one or more components of the blood vessel wall.
一名患艾滋病相关综合征（ARC）的患者出现了提示上升性脊髓病的暴发性神经综合征，并在入院后约48小时死亡。尸检时，有证据表明存在严重的坏死性血管炎，对神经系统影响最为严重，脊髓和马尾神经有多灶性出血性坏死。尽管在血管壁内及其周围主要为淋巴细胞-组织细胞浸润中可见到罕见的提示疱疹病毒感染的核内包涵体，但血管炎的确切病因并不明确。它可能代表血管壁一个或多个成分对艾滋病病毒感染的反应。
