Department of Anatomy and Cell Biology, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.
Exerc Sport Sci Rev. 2020 Apr;48(2):59-66. doi: 10.1249/JES.0000000000000217.
It is commonly assumed that beneficial adaptations in bone occur with vigorous exercise, yet any adaptive re/modeling in bone undergoing persistent overloading can be counteracted by superimposed inflammatory, compressive, and tensile loading-induced damage responses above thresholds of tissue fatigue failure and repair. This leads to a tenuous balance between achieving bone accrual and loss.
人们通常认为,剧烈运动能使骨骼产生有益的适应性改变,但在持续超负荷作用下发生的任何适应性重塑都可能被叠加的炎症、压缩和张应力引起的损伤反应所抵消,这些反应超过了组织疲劳失效和修复的阈值。这导致了在实现骨量增加和减少之间的微妙平衡。