Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece; Faculty of Health, University of Canberra, Australia.
Diabetes Res Clin Pract. 2020 Mar;161:108031. doi: 10.1016/j.diabres.2020.108031. Epub 2020 Jan 28.
To examine the association between dietary anti-inflammatory index (D-AII) and metabolic syndrome (MetS)prevalence, 10-year (2002-2012) diabetes, hypertension, hypercholesterolaemia incidence and 10-year transition from healthy (absence of all MetS traits, excluding waist circumference) to unhealthy metabolic status.
In 2001-2002, n = 1514 men and n = 1528 women (>18 years old) in Athens, Greece, free of cardiovascular disease were recruited. MetS was defined according to the revised NCEP ATP III (2005) or the IDF criteria or the harmonized criteria. The validated D-AII was calculated using a standardized procedure (range 10-77).
Inverse associations were observed between D-AII and transition from healthy to unhealthy metabolic status (Odds Ratio (OR) = 0.88 95% Confidence Interval (95%CI)(0.73, 0.98)) and diabetes (OR = 0.55, 95%CI(0.29, 0.77)). In women, D-AII was inversely associated with transition from healthy to unhealthy metabolic status (OR = 0.55, 95%CI(0.26, 0.90), diabetes (OR = 0.41, 95%CI(0.18, 0.64) and hypertension (OR = 0.75, 95%CI(0.20, 0.95), yet only with diabetes incidence in men (OR = 0.62, 95%CI(0.38, 0.93).
Diet with high anti-inflammatory load seems an effective preventive measure to retain a metabolically benign status, principally in terms of glycemic control.
研究饮食抗炎指数（D-AII）与代谢综合征（MetS）患病率、10 年（2002-2012 年）糖尿病、高血压、高胆固醇血症发病率以及从健康（无所有 MetS 特征，除腰围外）向不健康代谢状态 10 年转变的关系。
2001-2002 年，在希腊雅典招募了 n=1514 名男性和 n=1528 名女性（年龄>18 岁），这些人没有心血管疾病。MetS 根据修订的 NCEP ATP III（2005 年）或 IDF 标准或协调标准定义。使用标准化程序（范围为 10-77）计算了经过验证的 D-AII。
D-AII 与从健康向不健康代谢状态的转变呈负相关（比值比（OR）=0.88，95%置信区间（95%CI）（0.73，0.98））和糖尿病（OR=0.55，95%CI（0.29，0.77））。在女性中，D-AII 与从健康向不健康代谢状态的转变呈负相关（OR=0.55，95%CI（0.26，0.90））、糖尿病（OR=0.41，95%CI（0.18，0.64））和高血压（OR=0.75，95%CI（0.20，0.95））相关，但仅与男性糖尿病发病率相关（OR=0.62，95%CI（0.38，0.93））。
高抗炎负荷的饮食似乎是一种有效的预防措施，可以保持代谢良性状态，主要在血糖控制方面。
