Department of Pediatric Dentistry, Faculty of Dentistry, Universidade Federal de Minas Gerais (UFMG), Av. Antônio Carlos, 6627 Campus Pampulha, Belo Horizonte, MG, 31270-901, Brazil.
Department of Restorative Dentistry, Faculty of Dentistry, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.
Eur Arch Paediatr Dent. 2021 Feb;22(1):13-19. doi: 10.1007/s40368-020-00508-y. Epub 2020 Jan 31.
This study described and compared the oral characteristics of Brazilian individuals with mucopolysaccharidosis (MPS) and without MPS.
A cross-sectional study was performed with 29 individuals with MPS and 29 without MPS and their parents/guardians. The individuals were aged between 3 and 21 years and attended at two hospitals in Belo Horizonte, southeastern Brazil. The dental characteristics were evaluated by clinical examination of dental caries, gingivitis, malocclusion, dental anomalies and developmental defects of enamel. The parents/guardians answered a questionnaire about the sociodemographic and behavioural aspects of their children. The study was approved by the Research Ethics Committee of the Federal University of Minas Gerais.
The average age of the individuals was 13.9 years (± 7.2). The majority were male (58.6%), had black/brown skin (70.7%) and were from favored economic class (89.7%). Dental caries, gingivitis, malocclusion and dental anomalies were more prevalent in the MPS group (p < 0.05).
The individuals with MPS had a higher prevalence of oral diseases and dental anomalies than the group without MPS.
本研究描述并比较了巴西黏多糖贮积症（MPS）患者和非 MPS 患者的口腔特征。
这是一项横断面研究，纳入了 29 名 MPS 患者及其父母/监护人，以及 29 名非 MPS 患者及其父母/监护人。参与者年龄在 3 至 21 岁之间，均来自巴西东南部贝洛奥里藏特的两家医院。通过临床检查评估龋齿、牙龈炎、错颌畸形、牙齿异常和牙釉质发育缺陷等口腔特征。父母/监护人回答了一份关于孩子社会人口统计学和行为方面的问卷。本研究得到了米纳斯吉拉斯联邦大学研究伦理委员会的批准。
参与者的平均年龄为 13.9 岁（±7.2）。大多数参与者为男性（58.6%），皮肤为黑色/棕色（70.7%），来自经济条件较好的家庭（89.7%）。MPS 组的龋齿、牙龈炎、错颌畸形和牙齿异常更为常见（p<0.05）。
与非 MPS 组相比，MPS 患者的口腔疾病和牙齿异常发生率更高。
