使用 LiteMol Suite 可视化和分析蛋白质结构。

Visualization and Analysis of Protein Structures with LiteMol Suite.

机构信息

CEITEC-Central European Institute of Technology, Masaryk University Brno, Brno-Bohunice, Czech Republic.

National Centre for Biomolecular Research, Faculty of Science, Brno-Bohunice, Czech Republic.

出版信息

Methods Mol Biol. 2020;2112:1-13. doi: 10.1007/978-1-0716-0270-6_1.

DOI:10.1007/978-1-0716-0270-6_1

PMID:32006274

Abstract

LiteMol suite is an innovative solution that enables near-instant delivery of model and experimental biomacromolecular structural data, providing users with an interactive and responsive experience in all modern web browsers and mobile devices. LiteMol suite is a combination of data delivery services (CoordinateServer and DensityServer), compression format (BinaryCIF), and a molecular viewer (LiteMol Viewer). The LiteMol suite is integrated into Protein Data Bank in Europe (PDBe) and other life science web applications (e.g., UniProt, Ensemble, SIB, and CNRS services), it is freely available at https://litemol.org , and its source code is available via GitHub. LiteMol suite provides advanced functionality (annotations and their visualization, powerful selection features), and this chapter will describe their use for visual inspection of protein structures.

摘要

LiteMol 套件是一种创新的解决方案，可实现模型和实验生物大分子结构数据的近乎即时交付，为用户提供所有现代网络浏览器和移动设备中的交互和响应式体验。LiteMol 套件由数据传输服务（CoordinateServer 和 DensityServer）、压缩格式（BinaryCIF）和分子查看器（LiteMol Viewer）组成。LiteMol 套件集成到欧洲蛋白质数据库（PDBe）和其他生命科学网络应用程序（例如，UniProt、Ensemble、SIB 和 CNRS 服务）中，可在 https://litemol.org 免费获取，其源代码可通过 GitHub 获取。LiteMol 套件提供了高级功能（注释及其可视化、强大的选择功能），本章将描述其用于蛋白质结构的可视化检查。