Department of Orthopedics, Mount Sinai Hospital, New York, New York, USA.
Department of Neurosurgery, Mount Sinai Hospital, New York, New York, USA.
World Neurosurg. 2020 Jun;138:e26-e34. doi: 10.1016/j.wneu.2020.01.141. Epub 2020 Feb 14.
The predictive ability of Elixhauser Comorbidity Index (ECI) and Charlson Comorbidity Index (CCI) have been compared in orthopedic and gastrointestinal surgery; however, their predictive ability for complications secondary to spine surgery and posterior cervical decompression and fusion (PCDF) specifically is understudied. This study examines the predictive ability of the ECI and CCI for complications and morbidity following PCDF.
ECI and CCI were retrospectively computed for all PCDF cases in the National Inpatient Sample database from 2013 to 2014 and complications or morbidity were identified. C-statistics were used to analyze ECI and CCI predictive ability in a range of complications and compared with a base comorbidity model that included age, sex, race, and primary payer.
PCDF was performed in 46,700 hospitalizations between 2013 and 2014. The complications for which ECI was found to be a significantly better predictor included airway complications (69.16% superior to CCI), hemorrhagic anemia (79.04% superior), cardiac arrest (72.39% superior), pulmonary embolism (83.01% superior), sepsis (62.44% superior), septic shock (78.90% superior), urinary tract infection (63.53% superior), death (74.28% superior), any minor complication (75% superior), any major complication (133% superior), and any complication at all (63.72% superior). The complications for which neither the ECI Index nor the CCI proved superior were acute kidney injury, myocardial infarction, cerebrovascular accident, deep vein thrombosis, pneumonia, wound dehiscence, and superficial surgical-site infection following PCDF.
ECI showed superior predictive ability to the CCI in predicting 8 of the 18 complications that were analyzed and inferior in none.
Elixhauser 合并症指数(ECI)和 Charlson 合并症指数(CCI)在骨科和胃肠外科中的预测能力已被比较;然而,它们对脊柱手术和后路颈椎减压融合术(PCDF)后并发症的预测能力还研究得不够。本研究旨在探讨 ECI 和 CCI 对 PCDF 术后并发症和发病率的预测能力。
从 2013 年至 2014 年,在全国住院患者样本数据库中对所有接受 PCDF 的患者进行 ECI 和 CCI 的回顾性计算,并确定并发症或发病率。使用 C 统计量分析 ECI 和 CCI 在一系列并发症中的预测能力,并与包括年龄、性别、种族和主要支付者在内的基础合并症模型进行比较。
2013 年至 2014 年间,共进行了 46700 例 PCDF。发现 ECI 在预测以下并发症方面明显优于 CCI:气道并发症(69.16%优于 CCI)、出血性贫血(79.04%优于 CCI)、心脏骤停(72.39%优于 CCI)、肺栓塞(83.01%优于 CCI)、败血症(62.44%优于 CCI)、感染性休克(78.90%优于 CCI)、尿路感染(63.53%优于 CCI)、死亡(74.28%优于 CCI)、任何轻微并发症(75%优于 CCI)、任何主要并发症(133%优于 CCI)、以及任何并发症(63.72%优于 CCI)。ECI 指数和 CCI 均未证明优于以下并发症:急性肾损伤、心肌梗死、脑血管意外、深静脉血栓形成、肺炎、伤口裂开和 PCDF 后的浅表手术部位感染。
ECI 在预测分析的 18 种并发症中的 8 种并发症方面优于 CCI,而在任何一种并发症方面均不劣于 CCI。