Department of Otolaryngology, Hannover Medical School, Cluster of Excellence Hearing4all, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.
J Acoust Soc Am. 2020 Jan;147(1):350. doi: 10.1121/10.0000577.
Cochlear implantation is increasingly being used as a hearing-loss treatment for patients with residual hearing in the low acoustic frequencies. These patients obtain combined electric-acoustic stimulation (EAS). Substantial residual hearing and relatively long electrode arrays can lead to interactions between the electric and acoustic stimulation. This work investigated EAS interaction through psychophysical and electrophysiological measures. Moreover, cone-beam computed-tomography data was used to characterize the interaction along spatial cochlear locations. Psychophysical EAS interaction was estimated based on the threshold of audibility of an acoustic probe stimulus in the presence of a simultaneously presented electric masker stimulus. Intracochlear electrocochleography was used to estimate electrophysiological EAS interaction via the telemetry capability of the cochlear implant. EAS interaction was observed using psychophysical and electrophysiological measurements. While psychoacoustic EAS interaction was most pronounced close to the electrical stimulation site, electrophysiological EAS interaction was observed over a wider range of spatial cochlear locations. Psychophysical EAS interaction was significantly larger than electrophysiological EAS interaction for acoustic probes close to the electrode position.
人工耳蜗植入术越来越多地被用于治疗低频残余听力的听力损失患者。这些患者获得了电-声联合刺激（EAS）。大量的残余听力和相对较长的电极阵列可能导致电刺激和声学刺激之间的相互作用。这项工作通过心理物理和电生理测量来研究 EAS 相互作用。此外，还使用锥形束计算机断层扫描数据来描述沿着空间耳蜗位置的相互作用。基于存在同时呈现的电掩蔽刺激时声学探针刺激的可听阈，通过人工耳蜗植入物的遥测功能来估计 EAS 相互作用的心理物理 EAS 。通过人工耳蜗植入物的遥测功能来估计电生理 EAS 相互作用。虽然心理声学 EAS 相互作用在靠近电刺激部位时最为明显，但电生理 EAS 相互作用在更广泛的耳蜗空间位置上都有观察到。对于靠近电极位置的声学探针，心理物理 EAS 相互作用明显大于电生理 EAS 相互作用。
