Department of Ophthalmology, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, Jiangsu, China.
Nantong University, Nantong, Jiangsu, China.
BMC Ophthalmol. 2020 Feb 1;20(1):42. doi: 10.1186/s12886-020-1319-3.
Optical quality and macular thickness changing optical quality is rarely reported after femtosecond laser-assisted cataract surgery (FLACS). In current research, we evaluated optical quality recovery and distinct macular thickness changes after FLACS and phacoemulsification cataract surgery (PCS).
A total of 100 cataract patients (100 eyes) were included (50 eyes for the FLACS group and 50 eyes for the PCS group). Modulation transfer function (MTF), point spread function (PSF) and dysfunctional lens index (DLI) were measured by a ray-tracing aberrometer (iTrace). Uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (CDVA) were also assessed pre-operation,1 week and 1 month after surgery. The MTF values at spatial frequencies of 5, 10, 15, 20, 25 and 30 cycles/degree (c/d) were selected. We used optical coherence tomography (OCT) to assess the macular thickness of different regions pre-operatively and1month after the surgery.
In PCS group, we found the statistically significant differences between pre-operation and post-operation in DLI (p < 0.0001), PSF (strehl ratio, SR) (p = 0.027) and MTF (p = 0.028), but not intraocular pressure (IOP) (p = 0.857). The differences between pre-operation and post-operation for DLI (p = 0.031), SR (p = 0.01) and IOP (p = 0.03), but not MTF (p = 0.128) were also found in FLACS group. The differences were statistically significant when the spatial frequencies were at 5, 10 and 25 (p = 0.013, 0.031 and 0.048) between pre-operation and post-operation in PCS group but not FLACS group at 1 month. In PCS group, we found the differences between pre-operation and post-operation in nasal inter macular ring thickness (NIMRT) (p = 0.03), foveal volume (FV) (p = 0.034) and average retinal thickness (ART) (p = 0.025) but not FLACS group at 1 month.
FLACS is safe that did not cause significant increase of macular thickness in current study. However, it also cannot produce better optical quality. In contrast, PCS can produce macular thickness changes, but better optical quality recovery. The slightly retinal change may not affect optical quality.
飞秒激光辅助白内障手术（FLACS）后很少有报道称光学质量和黄斑厚度改变会改变光的质量。在目前的研究中，我们评估了 FLACS 和超声乳化白内障吸除术（PCS）后光学质量的恢复和明显的黄斑厚度变化。
共纳入 100 例白内障患者（100 只眼）（FLACS 组 50 只眼，PCS 组 50 只眼）。采用光线跟踪像差仪（iTrace）测量调制传递函数（MTF）、点扩散函数（PSF）和功能失调晶状体指数（DLI）。手术前、手术后 1 周和 1 个月分别评估未矫正远视力（UDVA）和矫正远视力（CDVA）。选择空间频率为 5、10、15、20、25 和 30 个周期/度（c/d）的 MTF 值。我们使用光学相干断层扫描（OCT）在术前和术后 1 个月评估不同区域的黄斑厚度。
在 PCS 组中，我们发现 DLI（p<0.0001）、PSF（斯特雷尔比，SR）（p=0.027）和 MTF（p=0.028）在术前和术后有统计学差异，但眼压（IOP）（p=0.857）无差异。FLACS 组也发现 DLI（p=0.031）、SR（p=0.01）和 IOP（p=0.03）术前和术后有差异，但 MTF 无差异（p=0.128）。在 PCS 组中，术后 1 个月时，空间频率为 5、10 和 25 时，术前和术后差异有统计学意义（p=0.013、0.031 和 0.048），但在 FLACS 组中无差异。在 PCS 组中，我们发现术前和术后鼻间黄斑环厚度（NIMRT）（p=0.03）、黄斑中心凹体积（FV）（p=0.034）和平均视网膜厚度（ART）（p=0.025）有差异，但在 FLACS 组中无差异。
FLACS 是安全的，在本研究中不会导致黄斑厚度的显著增加。然而，它也不能产生更好的光学质量。相比之下，PCS 可以产生黄斑厚度变化，但更好的光学质量恢复。轻微的视网膜变化可能不会影响光学质量。
