Eye Institute, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.
Sci Rep. 2018 Feb 19;8(1):3279. doi: 10.1038/s41598-018-21698-y.
Cataract surgery can cause macular thickness change. We used optical coherence tomography (OCT) to assess the macular thickness of different regions after femtosecond laser-assisted cataract surgery of age-related cataracts (ARC) and myopia cases with cataract (myopia group). Fifty eyes of 50 patients in ARC group and fifty eyes of 50 patients in myopia with cataract group were included. All study underwent femtosecond laser-assisted cataract surgery and macular thickness of was measured at pre-operation and 1 week, 1 month after surgery. There are significant differences of foveal thickness (P = 0.02), foveal volume (P = 0.02) and average retinal thickness (P = 0.02) between two groups before operation. In the myopia group, statistically significant differences were not found in postoperative macular thickness as compared with ARC group. There are differences in macular thickness between pre-operation and 1 month after operation when compared with nasal outer macular ring thickness (P = 0.022), foveal volume (P = 0.005) and average retinal thickness (P = 0.012) in ARC group. The study suggest that femtosecond laser-assisted cataract extraction is safe in myopia group that did not cause significant increase of macular thickness. However, an increased post-operative local macular thickness was recoded while comparing macular thickness with the baseline in ARC group.
白内障手术可引起黄斑厚度变化。我们使用光学相干断层扫描（OCT）评估年龄相关性白内障（ARC）和伴白内障的近视患者（近视组）的飞秒激光辅助白内障手术后不同区域的黄斑厚度。ARC 组纳入 50 例 50 眼，近视伴白内障组纳入 50 例 50 眼。所有患者均行飞秒激光辅助白内障手术，分别于术前、术后 1 周和 1 个月测量黄斑厚度。术前两组间中心凹厚度（P=0.02）、中心凹容积（P=0.02）和平均视网膜厚度（P=0.02）差异均有统计学意义。与 ARC 组相比，近视组术后黄斑厚度差异无统计学意义。ARC 组术后 1 个月与术前相比，鼻侧外黄斑环厚度（P=0.022）、中心凹容积（P=0.005）和平均视网膜厚度（P=0.012）差异均有统计学意义。研究表明，飞秒激光辅助白内障摘出术在近视组是安全的，不会导致黄斑厚度显著增加。然而，与 ARC 组相比，在比较黄斑厚度与基线时，记录到术后局部黄斑厚度增加。
