• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

小腿以下截肢后的自然史:超过 20 年的生存和假肢适配分析。

Natural History After Below-knee Amputation: Analysis of Survival and Prosthetic Fitting Over 2 Decades.

机构信息

Servicio de Angiología y Cirugía Vascular, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Barcelona, España.

Servicio de Angiología y Cirugía Vascular, Hospital del Mar, Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Barcelona, España.

出版信息

Cir Esp (Engl Ed). 2020 Aug-Sep;98(7):403-408. doi: 10.1016/j.ciresp.2019.11.007. Epub 2020 Jan 30.

DOI:10.1016/j.ciresp.2019.11.007
PMID:32007232
Abstract

INTRODUCTION

This study sought to evaluate the natural history of patients undergoing below-knee amputation (BKA) and compare their evolution over 2 decades, as well as survival predictors, prosthetic fitting, and contralateral amputation.

METHODS

Retrospective study of 209 consecutive patients (mean age 72.9 years; 68% males) who underwent BKA in 2 periods: 1996-2005 and 2006-2015. The fitting of prostheses, risk of contralateral amputation and survival, as well as their predictive factors, were assessed by survival analysis.

RESULTS

133 BKA were performed from 1996-2005 and 106 from 2006-2015. The etiology that motivated the BKA was acute ischemia (4.3%), chronic ischemia (34.0%), infection (9.1%) or mixed (chronic+infection, 52.6%), with no differences found between periods. Survival: mortality within one month=9.2%, one year=31.9%, 2 years=43.8% and 5 years=63.9%, with no significant differences between the 2 periods. Prosthetic: the fitting rate was 44.5% throughout the follow-up, with no significant differences between the two periods. 41.1% patients managed to walk. Contralateral amputation: 20.1% of the patients later required a major contralateral amputation, with no significant differences between the two periods.

CONCLUSIONS

In the last decade, fewer BKA have been performed probably, due to higher previous interventional revascularization. Despite this, the results of fitting, contralateral amputation or survival were not modified. In any case, the number of patients who are able to achieve ambulation is modest, so it emphasizes the need for an optimal selection of patients with BKA with the goal of prosthetic fitting.

摘要

引言

本研究旨在评估接受膝下截肢(BKA)患者的自然病史,并比较他们在 20 年内的演变情况,以及生存预测因素、假肢适配和对侧截肢。

方法

回顾性研究了 209 例连续患者(平均年龄 72.9 岁;68%为男性),他们在两个时期接受了 BKA:1996-2005 年和 2006-2015 年。通过生存分析评估了假肢适配、对侧截肢和生存的风险及其预测因素。

结果

1996-2005 年进行了 133 例 BKA,2006-2015 年进行了 106 例。导致 BKA 的病因是急性缺血(4.3%)、慢性缺血(34.0%)、感染(9.1%)或混合(慢性+感染,52.6%),两个时期之间没有差异。生存:一个月内死亡率=9.2%,一年内死亡率=31.9%,两年内死亡率=43.8%,五年内死亡率=63.9%,两个时期之间无显著差异。假肢:整个随访过程中,适配率为 44.5%,两个时期之间无显著差异。41.1%的患者能够行走。对侧截肢:20.1%的患者后来需要进行主要的对侧截肢,两个时期之间无显著差异。

结论

在过去的十年中,由于先前的介入血管重建术较高,可能进行了较少的 BKA。尽管如此,适配、对侧截肢或生存的结果并未改变。无论如何,能够实现行走的患者数量是适中的,因此强调了对 BKA 患者进行最佳选择的必要性,以实现假肢适配。

相似文献

1
Natural History After Below-knee Amputation: Analysis of Survival and Prosthetic Fitting Over 2 Decades.小腿以下截肢后的自然史:超过 20 年的生存和假肢适配分析。
Cir Esp (Engl Ed). 2020 Aug-Sep;98(7):403-408. doi: 10.1016/j.ciresp.2019.11.007. Epub 2020 Jan 30.
2
Rate of and Factors Associated with Ambulation After Unilateral Major Lower-Limb Amputation at an Urban US Tertiary-Care Hospital with a Multidisciplinary Limb Salvage Team.美国一家设有多学科肢体挽救团队的城市三级护理医院单侧下肢大截肢术后的行走率及相关因素
J Am Podiatr Med Assoc. 2017 Sep;107(5):355-364. doi: 10.7547/16-073.
3
Sex, age, and other barriers for prosthetic referral following amputation and the impact on survival.性别的影响、年龄因素和截肢术后对义肢转介的其他障碍,以及这些因素对存活率的影响。
J Vasc Surg. 2021 Nov;74(5):1659-1667. doi: 10.1016/j.jvs.2021.05.025. Epub 2021 May 31.
4
Functional outcome in a contemporary series of major lower extremity amputations.当代一系列下肢大截肢手术的功能结局。
J Vasc Surg. 2003 Jul;38(1):7-14. doi: 10.1016/s0741-5214(03)00092-2.
5
Prosthetic outcomes after amputation and the impact of mobility level on survival.截肢后的假体效果以及活动能力水平对生存率的影响。
J Vasc Surg. 2024 Sep;80(3):873-881. doi: 10.1016/j.jvs.2024.04.046. Epub 2024 Apr 24.
6
Is Reoperation Higher Than Expected after Below-the-knee Amputation? A Single-center Evaluation of Factors Associated with Reoperation at 1 Year.膝下截肢后再次手术的发生率高于预期吗?单中心对 1 年内再次手术相关因素的评估。
Clin Orthop Relat Res. 2021 Feb 1;479(2):324-331. doi: 10.1097/CORR.0000000000001455.
7
Below-Knee Amputation Failure and Poor Functional Outcomes Are Higher Than Predicted in Contemporary Practice.在当代实践中,膝下截肢失败率及不良功能结局高于预期。
Vasc Endovascular Surg. 2016 Nov;50(8):554-558. doi: 10.1177/1538574416682159. Epub 2016 Dec 14.
8
Prosthetic fitting and mortality after major lower extremity amputation.下肢大截肢后的假肢适配与死亡率。
J Vasc Surg. 2024 Aug;80(2):529-536. doi: 10.1016/j.jvs.2024.04.026. Epub 2024 May 20.
9
"Successful outcome" after below-knee amputation: an objective definition and influence of clinical variables.膝下截肢术后的“成功结局”:客观定义及临床变量的影响
Am Surg. 2008 Jul;74(7):607-12; discussion 612-3. doi: 10.1177/000313480807400707.
10
Re-amputations and mortality after below-knee, through-knee and above-knee amputations.膝下、膝部贯通及膝上截肢术后的再次截肢与死亡率
Dan Med J. 2018 Dec;65(12).