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2009-2014 年纽约市药物和酒精中毒死亡的多变量时空建模。

Multivariate spatiotemporal modeling of drug- and alcohol-poisoning deaths in New York City, 2009-2014.

机构信息

Department of Social and Behavioral Sciences, Yale School of Public Health, 60 College Street, LEPH 4th Floor, New Haven, CT 06510, United States; Department of Social and Behavioral Sciences, Harvard University, Boston, MA 02115, United States.

Department of Social and Behavioral Sciences, Harvard University, Boston, MA 02115, United States.

出版信息

Spat Spatiotemporal Epidemiol. 2020 Feb;32:100306. doi: 10.1016/j.sste.2019.100306. Epub 2019 Nov 11.

Abstract

Drug- and alcohol-poisoning deaths remain current public health problems. Studies to date have typically focused on individual-level predictors of drug overdose deaths, and there remains a limited understanding of the spatiotemporal patterns and predictors of the joint outcomes. We use a hierarchical Bayesian spatiotemporal multivariate Poisson regression model on data from (N = 167) ZIP-codes between 2009 and 2014 in New York City to examine the spatiotemporal patterns of the joint occurrence of drug (opioids) and alcohol-poisoning deaths, and the covariates associated with each outcome. Results indicate that rates of both outcomes were highly positively correlated across ZIP-codes (cross-correlation: 0.57, 95% credible interval (CrI): 0.29, 0.77). ZIP-codes with a higher prevalence of heavy drinking had higher alcohol-poisoning deaths (relative risk (RR):1.63, 95% CrI: 1.26, 2.05) and drug-poisoning deaths (RR: 1.29, 95% CrI: 1.03, 1.59). These spatial patterns may guide public health planners to target specific areas to address these co-occurring epidemics.

摘要

药物和酒精中毒死亡仍然是当前的公共卫生问题。迄今为止的研究通常侧重于药物过量死亡的个体水平预测因素,对于联合结果的时空模式和预测因素仍知之甚少。我们使用分层贝叶斯时空多变量泊松回归模型,对 2009 年至 2014 年纽约市(N=167)ZIP 编码的数据进行分析,以检查药物(阿片类药物)和酒精中毒死亡联合发生的时空模式,以及与每个结果相关的协变量。结果表明,ZIP 编码内两种结果的发生率在空间上高度正相关(交叉相关:0.57,95%可信区间(CrI):0.29,0.77)。酗酒发生率较高的 ZIP 编码地区,酒精中毒死亡(相对风险(RR):1.63,95% CrI:1.26,2.05)和药物中毒死亡(RR:1.29,95% CrI:1.03,1.59)的发生率更高。这些空间模式可能指导公共卫生规划者针对特定地区解决这些同时发生的流行病。

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