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寻求泌尿外科治疗的男性中佩罗尼氏病的患病率、危险因素及勃起功能障碍

Prevalence, Risk Factors, and Erectile Dysfunction Associated With Peyronie's Disease Among Men Seeking Urological Care.

作者信息

Segundo Antonio, Glina Sidney

机构信息

Department of Urology, Faculdade Medicina ABC, Santo André, Brazil.

Department of Urology, Faculdade Medicina ABC, Santo André, Brazil.

出版信息

Sex Med. 2020 Jun;8(2):230-236. doi: 10.1016/j.esxm.2019.11.002. Epub 2020 Jan 30.

DOI:10.1016/j.esxm.2019.11.002
PMID:32007472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7261680/
Abstract

INTRODUCTION

Peyronie's disease (PD) is a connective tissue disorder of the penis characterized by an abnormality in collagen structure of penile tunica albuginea.

AIM

We sought to investigate the prevalence, risk factors, and the relationship between erectile dysfunction (ED) and PD in male patients aged 30-80 years seeking urological care.

METHODS

This is a cross-sectional study using data collected from October 2016 to October 2017 in an outpatient clinic associated with the Brazilian Public Health System. All men aged 30 to 80 years were invited to participate. Data collected were related to the clinical history and sexual habits of patients using the International Index of Erectile Function, in addition to the physical examination of the penis and laboratory parameters.

MAIN OUTCOME MEASURE

Descriptive statistics and multivariate logistic regression models tested the prevalence, risk factors, and the relationship between ED and PD in male patients.

RESULTS

The study included 656 individuals, who were distributed as per age, marital status, race, educational level, and income. Of these participants, 86 (13.11%) presented with fibrous plaques compatible with PD at the physical examination. Among the risk factors evaluated, PD was associated with diabetes, smoking, and obesity in 43.02, 64.17, and 26.74% of patients, respectively. The presence of penile plaques compatible with PD was more prevalent in men with ED, history of penile trauma, and complaint of penile deformity. There was a higher prevalence of plaques in the distal penis.

CONCLUSION

The PD among the studied population was associated with risk factors such as diabetes, smoking, and obesity. Other clinical characteristics, such as history of penile trauma, penile deformity, and ED, were reported in patients with PD. There was a higher prevalence of plaques in the distal penis, specifically in the corona of the glans penis. The prevalence of PD was different from that in the published literature, our results show that numbers thus more studies are needed. Segundo A, Glina S. Prevalence, Risk Factors, and Erectile Dysfunction Associated With Peyronie's Disease Among Men Seeking Urological Care. Sex Med 2020;8:230-236.

摘要

引言

佩罗尼氏病(PD)是一种阴茎结缔组织疾病,其特征为阴茎白膜的胶原结构异常。

目的

我们试图调查在寻求泌尿科治疗的30至80岁男性患者中,佩罗尼氏病的患病率、危险因素以及勃起功能障碍(ED)与佩罗尼氏病之间的关系。

方法

这是一项横断面研究,使用了2016年10月至2017年10月在巴西公共卫生系统所属门诊收集的数据。邀请了所有30至80岁的男性参与。收集的数据涉及患者的临床病史和性习惯(使用国际勃起功能指数),此外还包括阴茎的体格检查和实验室参数。

主要观察指标

描述性统计和多变量逻辑回归模型对男性患者中佩罗尼氏病的患病率、危险因素以及勃起功能障碍与佩罗尼氏病之间的关系进行了测试。

结果

该研究纳入了656名个体,这些个体按年龄、婚姻状况、种族、教育程度和收入进行了分布。在这些参与者中,86人(13.11%)在体格检查时出现了与佩罗尼氏病相符的纤维斑块。在评估的危险因素中,佩罗尼氏病分别与43.02%的糖尿病患者、64.17%的吸烟者和26.74%的肥胖患者相关。与佩罗尼氏病相符的阴茎斑块在勃起功能障碍患者、有阴茎创伤史的患者以及有阴茎畸形主诉的患者中更为普遍。阴茎远端的斑块患病率更高。

结论

在所研究的人群中,佩罗尼氏病与糖尿病、吸烟和肥胖等危险因素相关。佩罗尼氏病患者还存在其他临床特征,如阴茎创伤史、阴茎畸形和勃起功能障碍。阴茎远端,特别是阴茎头冠状沟处的斑块患病率更高。佩罗尼氏病的患病率与已发表文献中的不同,我们的结果表明需要更多的研究。Segundo A, Glina S.寻求泌尿科治疗的男性中佩罗尼氏病的患病率、危险因素及勃起功能障碍。性医学2020;8:230 - 236。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ced9/7261680/770c5ae141d9/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ced9/7261680/729a30c19d8d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ced9/7261680/770c5ae141d9/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ced9/7261680/729a30c19d8d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ced9/7261680/770c5ae141d9/gr2.jpg

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