Center for Applied Neuroscience, University of Cyprus, Nicosia, Cyprus.
KIOS Innovation & Research Center of Excellence, University of Cyprus, Nicosia, Cyprus.
NeuroRehabilitation. 2020;46(1):109-118. doi: 10.3233/NRE-192963.
Moderate-to-severe traumatic brain injury (TBI) leads to significant neuropsychological impairment, further affecting quality of life (QOL).
Investigate the effects of chronic moderate-to-severe TBI on Executive Functions (EF), Self-awareness (SA), QOL, and the associations between them.
33 males with moderate-to-severe TBI (ages 18-51; time since injury 1-19 years) were compared to 24 non-injured males, matched on age and education. EF measures included the Rey Complex Figure Test (copy), the Trail Making Test A & B, the Symbol Digits Modalities Test, and the Control Oral Word Association Test. SA was assessed using the Dysexecutive Questionnaire Revised, and the Self-Regulation Skills Interview. QOL and health-realted QOL were assessed using the WHOQOL-BREF and the QOL after Brain Injury, respectively.
TBI participants scored lower on EF, and SA, reported less satisfaction regarding physical health and greater satisfaction with environmental support, than controls. TBI survivors scoring lower on EF, exhibited lower SA. Lower SA correlated with greater satisfaction regarding cognitive skills, self-perception, and overall HRQOL. Lower EF performance correlated with greater satisfaction in social relationships.
The long-term effects of TBI on EF, SA and QOL seem to support the role of EF and SA on QOL, and therefore, the need for personalized interventions in improving recovery outcome.
中重度创伤性脑损伤（TBI）会导致严重的神经心理障碍，进一步影响生活质量（QOL）。
研究慢性中重度 TBI 对执行功能（EF）、自我意识（SA）、QOL 的影响及其之间的关系。
33 名中重度 TBI 男性（年龄 18-51 岁；受伤时间 1-19 年）与 24 名非损伤男性进行比较，匹配年龄和教育程度。EF 测量包括 Rey 复杂图形测试（复制）、TMT A&B 测试、符号数字模式测试和控制口头联想测试。SA 使用修正后的执行功能问卷和自我调节技能访谈进行评估。使用 WHOQOL-BREF 和脑损伤后生活质量量表分别评估 QOL 和健康相关 QOL。
TBI 参与者在 EF 和 SA 方面的得分较低，与对照组相比，他们对身体健康的满意度较低，对环境支持的满意度较高。EF 得分较低的 TBI 幸存者表现出较低的 SA。较低的 SA 与认知技能、自我认知和整体 HRQOL 的更高满意度相关。较低的 EF 表现与社会关系满意度的提高相关。
TBI 对 EF、SA 和 QOL 的长期影响似乎支持 EF 和 SA 对 QOL 的作用，因此需要进行个性化干预以改善康复效果。
