Zhu Hongzhang, Feng Shi-Ting, Zhang Xingqi, Ke Zunfu, Zeng Ruixi, Yang Xufeng, Han Jiande, Zhou Hui
Department of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Department of Dermatology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
Curr Med Imaging Rev. 2019;15(9):906-910. doi: 10.2174/1573405614666181005113448.
Cutis Verticis Gyrata (CVG) is a rare skin disease caused by overgrowth of the scalp, presenting as cerebriform folds and wrinkles. CVG can be classified into two forms: primary (essential and non-essential) and secondary. The primary non-essential form is often associated with neurological and ophthalmological abnormalities, while the primary essential form occurs without associated comorbidities.
We report on a rare case of primary essential CVG with a 4-year history of normal-colored scalp skin mass in the parietal-occipital region without symptom in a 34-year-old male patient, retrospectively summarizing his pathological and Computer Tomography (CT) and magnetic resonance imaging (MRI) findings. The major clinical observations on the CT and MR sectional images include a thickened dermis and excessive growth of the scalp, forming the characteristic scalp folds. With the help of CT and MRI Three-dimensional (3D) reconstruction techniques, the characteristic skin changes could be displayed intuitively, providing more evidence for a diagnosis of CVG. At the 5-year followup, there were no obvious changes in the lesion.
Based on our observations, we propose that not all patients with primary essential CVG need surgical intervention, and continuous clinical observation should be an appropriate therapy for those in stable condition.
头皮回状颅皮（CVG）是一种由头皮过度生长引起的罕见皮肤病，表现为脑回样褶皱。CVG可分为两种类型：原发性（特发性和非特发性）和继发性。原发性非特发性类型常与神经和眼科异常相关，而原发性特发性类型则无相关合并症。
我们报告了一例罕见的原发性特发性CVG病例，一名34岁男性患者，顶枕部头皮有一正常颜色的肿物，病史4年，无症状。回顾性总结其病理及计算机断层扫描（CT）和磁共振成像（MRI）结果。CT和MR断层图像上的主要临床观察结果包括真皮增厚和头皮过度生长，形成特征性的头皮褶皱。借助CT和MRI三维（3D）重建技术，可以直观地显示特征性皮肤变化，为CVG的诊断提供更多证据。在5年的随访中，病变无明显变化。
根据我们的观察，我们提出并非所有原发性特发性CVG患者都需要手术干预，对于病情稳定的患者，持续临床观察应是一种合适的治疗方法。
