Faculty of Biological, Medical and Human Sciences, Maternal and Fetal Health Research Centre, School of Medical Sciences, University of Manchester, Manchester Academic Health Science Centre, St. Mary's Hospital, Central Manchester University Hospitals NHS Foundation Trust, 5th Floor (Research), Oxford Road, Manchester M13 9WL, UK.
Faculty of Biological, Medical and Human Sciences, Maternal and Fetal Health Research Centre, School of Medical Sciences, University of Manchester, Manchester Academic Health Science Centre, St. Mary's Hospital, Central Manchester University Hospitals NHS Foundation Trust, 5th Floor (Research), Oxford Road, Manchester M13 9WL, UK.
Obstet Gynecol Clin North Am. 2020 Mar;47(1):183-196. doi: 10.1016/j.ogc.2019.10.005. Epub 2019 Dec 18.
Because of the critical role that placental structure and function plays during pregnancy, abnormal placental structure and function is closely related to stillbirth: when an infant dies before birth. However, understanding the role of the placental and specific lesions is incomplete, in part because of the variation in definitions of lesions and in classifying causes of stillbirths. Nevertheless, placental abnormalities are seen more frequently in stillbirths than live births, with placental abruption, chorioamnionitis, and maternal vascular malperfusion most commonly reported. Critically, some placental lesions affect the management of subsequent pregnancies. Histopathological examination of the placenta is recommended following stillbirth.
由于胎盘结构和功能在妊娠期间起着至关重要的作用,因此异常的胎盘结构和功能与死胎密切相关:当婴儿在出生前死亡时。然而,人们对胎盘的作用和具体病变的了解并不完整,部分原因是病变的定义和死产原因的分类存在差异。尽管如此,胎盘异常在死产中比活产中更为常见,最常报告的是胎盘早剥、绒毛膜羊膜炎和母体血管功能不全。重要的是,一些胎盘病变会影响后续妊娠的管理。建议在死胎后对胎盘进行组织病理学检查。