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电抽搐治疗在重度双相混合状态治疗中的作用。

The Role of Electroconvulsive Therapy in the Treatment of Severe Bipolar Mixed State.

机构信息

Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 67, Pisa 56100, Italy; Psychiatry Unit 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.

Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 67, Pisa 56100, Italy.

出版信息

Psychiatr Clin North Am. 2020 Mar;43(1):187-197. doi: 10.1016/j.psc.2019.10.010. Epub 2019 Dec 2.

DOI:10.1016/j.psc.2019.10.010
PMID:32008684
Abstract

Electroconvulsive therapy (ECT) results effective in two-thirds of the patients with severe and drug-resistant mixed states. The episode duration is the main predictor of nonresponse. This practice may increase the risk of mood destabilization and chronic complications and may decrease the chance of recovery in many patients. Compared with the burden of neurologic and metabolic side effects associated with long-term use of complex pharmacologic regimens, ECT should be considered a safe option with a very low incidence of severe adverse events and a long-term nondestabilizing effect.

摘要

电抽搐治疗(ECT)对三分之二的重度和耐药混合状态患者有效。发作持续时间是无反应的主要预测因素。这种做法可能会增加情绪不稳定和慢性并发症的风险,并可能降低许多患者的康复机会。与长期使用复杂药物治疗方案相关的神经和代谢副作用的负担相比,ECT 应被视为一种安全的选择,其严重不良事件发生率非常低,且长期无稳定作用。

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