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1例采用电休克治疗的谵妄性躁狂病例

A Case of Delirious Mania Treated with Electroconvulsive Therapy.

作者信息

Tripodi Beniamino, Carbone Manuel Glauco, Matarese Irene, Lattanzi Lorenzo, Medda Pierpaolo

机构信息

Department of Mental Health and Addictions, Division of Psychiatry, ASST Crema, Via Largo Ugo Dossena 2, 26013 Crema, CR, Italy.

Pisa-School of Experimental and Clinical Psychiatry, University of Pisa, Via Roma 57, 56100 Pisa, PI, Italy.

出版信息

Life (Basel). 2023 Jul 12;13(7):1544. doi: 10.3390/life13071544.

Abstract

(1) Background: Delirious mania is a neuropsychiatric condition characterized by the rapid onset of delirium, psychosis, and mania. Due to the presence of catatonic signs and symptoms, some authors considered this syndrome to be a specific excited catatonia subtype. Usually, delirious mania is responsive to intravenous benzodiazepines (BZDs) or to electroconvulsive therapy (ECT). (2) Methods: In the present study, we describe the case of a 64-year-old woman with a diagnosis of recurrent major depressive disorder. We assessed the severity of the clinical picture and the response to ECT treatment with the Bush-Francis Catatonia Rating Scale (BFCRS). (3) Results: After eleven sessions of ECT, the patient presented a reduced BFCRS total score, with a resolution of the autonomic abnormalities (temperature, respiratory, and heart rate). (4) Conclusions: These data demonstrate how important it is to diagnose this syndrome as soon as possible to set up an effective therapy, avoiding the use of antipsychotic drugs and preventing potentially fatal complications. The initial administration of BZDs IV and the subsequent ECT application, associated with intensive care of life-threatening general medical conditions, guaranteed us a good level of efficacy in obtaining a complete resolution of the clinical picture.

摘要

(1) 背景:谵妄性躁狂是一种神经精神疾病,其特征为谵妄、精神病和躁狂迅速发作。由于存在紧张症的体征和症状,一些作者认为该综合征是一种特定的激越性紧张症亚型。通常,谵妄性躁狂对静脉注射苯二氮䓬类药物(BZD)或电休克治疗(ECT)有反应。(2) 方法:在本研究中,我们描述了一名64岁诊断为复发性重度抑郁症的女性病例。我们使用布什 - 弗朗西斯紧张症评定量表(BFCRS)评估临床症状的严重程度以及对ECT治疗的反应。(3) 结果:经过11次ECT治疗后,患者的BFCRS总分降低,自主神经异常(体温、呼吸和心率)得到缓解。(4) 结论:这些数据表明尽早诊断该综合征以建立有效治疗、避免使用抗精神病药物并预防潜在致命并发症是多么重要。静脉注射BZD并随后应用ECT,同时对危及生命的一般医疗状况进行重症监护,确保我们在完全消除临床症状方面获得了良好的疗效水平。

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