火环：儿童期创伤、情绪反应与心境障碍中的混合状态。
The Ring of Fire: Childhood Trauma, Emotional Reactivity, and Mixed States in Mood Disorders.
机构信息
Sapienza School of Medicine and Psychology, Sant'Andrea University Hospital, UOC Psichiatria, Via di Grottarossa, 1035-1039, Rome 00189, Italy; ICAHN School of Medicine and Mount Sinai, New York, NY, USA; Centro Lucio Bini, Via Crescenzio 42, Rome 00193, Italy.
Centro Lucio Bini, Via Crescenzio 42, Rome 00193, Italy; School of Medicine and Psychology, NESMOS Department (Neuroscience, Mental Health and Sensory Organs) Sapienza University, Sant'Andrea Hospital, Via di Grottarossa 1035-1038, Rome 00189, Italy.
出版信息
Psychiatr Clin North Am. 2020 Mar;43(1):69-82. doi: 10.1016/j.psc.2019.10.007. Epub 2019 Nov 28.
Childhood trauma (CT) is strongly associated with bipolar disorder, possibly through emotional hyperreactivity (EH). Mixed symptoms/states (MSs) are associated with increased illness severity. The authors tested through a systematic review the association between CT and MSs. The authors systematically looked for studies exploring associations between MSs and CT, CT and EH, and EH and MSs. Most literature agrees that MSs are associated with CT; the latter was found to be associated to EH, which is in turn associated with MSs. The literature supports an association between CT and later development of MSs, possibly mediated through EH.
儿童期创伤（CT）与双相情感障碍密切相关，可能通过情绪过度反应（EH）实现。混合症状/状态（MSs）与疾病严重程度增加有关。作者通过系统综述检验 CT 与 MSs 之间的关联。作者系统地寻找研究 MSs 与 CT、CT 与 EH 以及 EH 与 MSs 之间关联的研究。大多数文献都认为 MSs 与 CT 有关；EH 与 CT 有关，EH 又与 MSs 有关。文献支持 CT 与随后 MSs 发展之间的关联，可能通过 EH 介导。
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