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脊髓梅毒瘤的诊断与治疗:一例报告

Diagnosis and Treatment of Spinal Syphilitic Gumma: A Case Report.

作者信息

Cui Linyang, Xu Zushan, Hou Hongjun

机构信息

Department of Radiology, Weihai Central Hospital, Weihai, China.

出版信息

Front Neurol. 2020 Jan 15;10:1352. doi: 10.3389/fneur.2019.01352. eCollection 2019.

DOI:10.3389/fneur.2019.01352
PMID:32010040
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6974620/
Abstract

Neurosyphilis, which is caused by , is a rare sexually transmitted disease involving the central nervous system (CNS). Among all the sub-categories, spinal syphilitic gumma is extremely rare. In previous literature, limited cases of spinal syphilitic gumma have been reported, most of which underwent surgery treatment. In this study, we reported a 46-year-old man, who presented with 5-day numbness of bilateral lower limbs, lower back pain, and irregular defecation. Magnetic resonance imaging (MRI) revealed a homogeneous peripheral enhancement and intramedullary nodule at the T7 level with extensive thoracic cord edema. Combining with laboratory examination results, the syphilitic gumma was considered. One month after the administration of penicillin G, the symptoms vanished. Six months later, MRI indicated no intramedullary nodule.

摘要

神经梅毒是一种由[病原体未提及]引起的罕见性传播疾病,累及中枢神经系统(CNS)。在所有亚型中,脊髓梅毒瘤极为罕见。在既往文献中,脊髓梅毒瘤的报道病例有限,其中大多数接受了手术治疗。在本研究中,我们报告了一名46岁男性,他出现双侧下肢麻木5天、下背部疼痛及大便不规律。磁共振成像(MRI)显示T7水平有均匀的外周强化和髓内结节,伴有广泛的胸段脊髓水肿。结合实验室检查结果,考虑为梅毒瘤。给予青霉素G治疗1个月后,症状消失。6个月后,MRI显示无髓内结节。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fef9/6974620/b237c715d4a2/fneur-10-01352-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fef9/6974620/09b75d060523/fneur-10-01352-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fef9/6974620/c87a442e35df/fneur-10-01352-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fef9/6974620/b237c715d4a2/fneur-10-01352-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fef9/6974620/09b75d060523/fneur-10-01352-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fef9/6974620/c87a442e35df/fneur-10-01352-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fef9/6974620/b237c715d4a2/fneur-10-01352-g0003.jpg

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本文引用的文献

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2
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Ann Clin Lab Sci. 2019 Mar;49(2):265-270.
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Spinal Intramedullary Syphilitic Gumma: An Unusual Presentation of Neurosyphilis.脊髓髓内梅毒瘤:一种罕见的神经梅毒表现。
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NMC Case Rep J. 2021 Sep 16;8(1):637-643. doi: 10.2176/nmccrj.cr.2021-0098. eCollection 2021.
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Case Rep Infect Dis. 2021 Jun 2;2021:5533686. doi: 10.1155/2021/5533686. eCollection 2021.
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