Parikh Rohan P, Washimkar Sunil, Deshmukh Pradeep, Deshpande Mukund, Beedkar Amey, Talaviya Bhavesh, Maske Mahendra
Olympus Hospital, Vidhyanagar Main Road, Rajkot, Pin-360002 Gujarat, Ahmedabad, India.
Open Access Maced J Med Sci. 2019 Oct 14;7(21):3603-3607. doi: 10.3889/oamjms.2019.780. eCollection 2019 Nov 15.
To study clinical and epidemiological parameters of patients undergoing percutaneous coronary intervention (PCI) and to follow them up for understanding the outcomes of the procedure.
This is a retrospective data analysis of 862 patients who underwent PCI from January 2016 to November 2017.
Out of 862 patients, 611 (70.88%) were male & 251 (29.12%) were female, with the mean age being 55. 243 (28.19%) were diabetic, 470 (54.52%) were hypertensive, 158 (18.32%) patients were tobacco chewer, 215 (24.92%) were smokers and 111 (12.87%) were alcoholic. 636 (73.78%) patients had STEMI, 153 (17.74%) had NSTE-ACS, 61 (7.07%) had CSA.578 (67.05%) were SVD, 262 (30.39%) were DVD and 19 (2.20%) were TVD. Out of SVD, 350 (60.55%) patients had LAD involvement and among DVD patients, LAD and RCA were most commonly involved in 107 (40.83%) patients. On follow-up of mean 604.42 days (minimum 236 days, maximum 909 days), 2 (0.23%) episodes of subacute stent thrombosis occurred and 11 (1.27%) patients had ISR but no mortality was reported.
The study shows affection of young population predominately and genders inequality, suggesting primarily male disease. PCI is often sought in ACS and CSA is predominately treated medically. Thrombolysis remains the first treatment received by STEMI patients. SVD is the most common angiographic diagnosis with LAD predominately affected vessel. This real world-data on clopidogrel with aspirin as dual antiplatelet therapy and second-generation stent shows negligible event of stent thrombosis and ISR.
Due to non-invasive follow-up, the exact amount of stent restenosis cannot be calculated.
This real world-data on clopidogrel with aspirin as dual antiplatelet therapy and second-generation stent shows negligible event of stent thrombosis and ISR. This can help reduce the cost burden on society and help better distribution of health budget.
研究接受经皮冠状动脉介入治疗(PCI)患者的临床和流行病学参数,并对其进行随访以了解该手术的结果。
这是一项对2016年1月至2017年11月期间接受PCI的862例患者进行的回顾性数据分析。
862例患者中,男性611例(70.88%),女性251例(29.12%),平均年龄为55岁。243例(28.19%)患有糖尿病,470例(54.52%)患有高血压,158例(18.32%)嚼烟草,215例(24.92%)吸烟,111例(12.87%)饮酒。636例(73.78%)患者患有ST段抬高型心肌梗死(STEMI),153例(17.74%)患有非ST段抬高型急性冠状动脉综合征(NSTE-ACS),61例(7.07%)患有冠状动脉痉挛(CSA)。578例(67.05%)为单支血管病变(SVD),262例(30.39%)为双支血管病变(DVD),19例(2.20%)为三支血管病变(TVD)。在SVD患者中,350例(60.55%)累及左前降支(LAD),在DVD患者中,LAD和右冠状动脉(RCA)最常受累,共107例(40.83%)。在平均604.42天(最短236天,最长9天)的随访中,发生2例(0.23%)亚急性支架血栓形成,11例(1.27%)患者发生支架内再狭窄,但未报告死亡病例。
该研究表明主要影响年轻人群且存在性别不平等,提示这主要是一种男性疾病。PCI常用于急性冠状动脉综合征(ACS),而冠状动脉痉挛(CSA)主要采用药物治疗。溶栓仍然是STEMI患者接受的首要治疗方法。单支血管病变(SVD)是最常见的血管造影诊断结果,并以LAD为主要受累血管。关于氯吡格雷与阿司匹林作为双联抗血小板治疗以及第二代支架的这一真实世界数据显示,支架血栓形成和支架内再狭窄的发生率可忽略不计。
由于采用非侵入性随访,无法计算支架再狭窄的确切数量。
关于氯吡格雷与阿司匹林作为双联抗血小板治疗以及第二代支架的这一真实世界数据显示,支架血栓形成和支架内再狭窄的发生率可忽略不计。这有助于减轻社会的成本负担,并有助于更好地分配卫生预算。