Wada Paul Y, Lee-Rodriguez Christian, Hung Yun-Yi, Skarbinski Jacek
Internal Medicine Residency Program, Oakland Medical Center, Kaiser Permanente Northern California, Oakland, California, USA.
Division of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Open Forum Infect Dis. 2020 Jan 12;7(1):ofaa015. doi: 10.1093/ofid/ofaa015. eCollection 2020 Jan.
Active tuberculosis (TB) is preventable. To quantify the potential value of prevention, we assessed active TB burden in a large health system from 1997 to 2016. Compared with a matched non-TB cohort, patients with active TB had higher mortality (8.4% vs 1.3%), mean number of hospitalizations (0.55 vs 0.10), emergency department visits (0.78 vs 0.28), and outpatient visits (14.6 vs 5.9) in the first year. TB-associated hospital use (mean number of hospitalizations and total length of stay) increased from 1997-2000 compared with 2013-2016 despite decreasing active TB incidence. Active TB is associated with high mortality and health care utilization and has remained stable or increased over time.
活动性结核病（TB）是可预防的。为了量化预防的潜在价值，我们评估了1997年至2016年期间一个大型医疗系统中的活动性结核病负担。与匹配的非结核病队列相比，活动性结核病患者在第一年的死亡率更高（8.4%对1.3%）、平均住院次数更多（0.55对0.10）、急诊就诊次数更多（0.78对0.28）以及门诊就诊次数更多（14.6对5.9）。尽管活动性结核病发病率有所下降，但与结核病相关的医院使用情况（平均住院次数和总住院时间）在1997 - 2000年相比2013 - 2016年有所增加。活动性结核病与高死亡率和医疗保健利用率相关，并且随着时间的推移一直保持稳定或有所增加。
