Department of Chemistry, Indian Institute of Technology Ropar, Nangal Road, Rupnagar, Punjab, 140001, India.
Chem Asian J. 2020 Mar 16;15(6):651-672. doi: 10.1002/asia.201901744. Epub 2020 Feb 18.
The N-centered radical directed remote C-H bond functionalization via hydrogen-atom-transfer at distant sites has developed as an enormous potential tool for the organic synthetic chemists. Unactivated and remote secondary and tertiary, as well as selected primary C-H bonds, can be utilized for functionalization by following these methodologies. The synthesis of the heterocyclic scaffolds provides them extra attention for the modern days' developments in this field of unactivated remote C-H bonds functionalizations.
N 中心自由基导向的远程 C-H 键功能化通过氢原子转移在远离的位点发展成为有机合成化学家的一个巨大潜力工具。通过遵循这些方法，未活化的和远程的仲和叔 C-H 键，以及选择的伯 C-H 键，都可以被用于功能化。杂环支架的合成为这个未活化远程 C-H 键功能化领域的现代发展提供了额外的关注。
